Entrez Gene

Basic Information
Gene ID	1917
Name	EEF1A2
Synonymous	eukaryotic translation elongation factor 1 alpha 2;EEF1A2;eukaryotic translation elongation factor 1 alpha 2
Definition	elongation factor 1-alpha 2\|eukaryotic elongation factor 1 A-2\|statin-S1
Position	20q13.3
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC confirmed somatic mutation [Top]

c.1012G>T; p.A338S; 20:63490496-63490496	breast	carcinoma	Substitution - Missense
c.594T>C; p.G198G; 20:63494832-63494832	breast	carcinoma	Substitution - coding silent
c.917A>T; p.D306V; 20:63490591-63490591	breast	carcinoma	Substitution - Missense
c.1296G>A; p.T432T; 20:63488394-63488394	breast	carcinoma	Substitution - coding silent
c.30C>G; p.I10M; 20:63497734-63497734	breast	carcinoma	Substitution - Missense
c.252G>C; p.K84N; 20:63495928-63495928	central_nervous_system; brain	glioma	Substitution - Missense
c.783G>A; p.T261T; 20:63490725-63490725	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.783G>A; p.T261T; 20:63490725-63490725	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1112A>G; p.K371R; 20:63489070-63489070	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.1082T>C; p.I361T; 20:63489100-63489100	central_nervous_system; brain	glioma; astrocytoma_Grade_II	Substitution - Missense
c.592G>A; p.G198S; 20:63494834-63494834	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.1078G>A; p.V360I; 20:63489104-63489104	central_nervous_system; brain	glioma; astrocytoma_Grade_II	Substitution - Missense
c.525C>T; p.S175S; 20:63494901-63494901	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.841G>A; p.A281T; 20:63490667-63490667	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.97G>A; p.G33S; 20:63497667-63497667	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.663C>T; p.G221G; 20:63493246-63493246	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.948G>A; p.S316S; 20:63490560-63490560	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.271G>A; p.D91N; 20:63495909-63495909	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.504C>T; p.D168D; 20:63494922-63494922	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1027C>A; p.Q343K; 20:63490481-63490481	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.1253A>C; p.Y418S; 20:63488929-63488929	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.138G>A; p.A46A; 20:63497626-63497626	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.841G>A; p.A281T; 20:63490667-63490667	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.594T>C; p.G198G; 20:63494832-63494832	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.615C>T; p.S205S; 20:63494811-63494811	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.499T>C; p.Y167H; 20:63494927-63494927	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.306G>A; p.M102I; 20:63495874-63495874	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.526G>A; p.A176T; 20:63494900-63494900	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1217C>T; p.P406L; 20:63488965-63488965	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.391G>A; p.G131R; 20:63495035-63495035	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1335C>T; p.S445S; 20:63488355-63488355	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.904G>A; p.A302T; 20:63490604-63490604	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.714delC; p.T239fs*40; 20:63493195-63493195	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.454G>A; p.V152M; 20:63494972-63494972	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.137C>A; p.A46E; 20:63497627-63497627	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.842C>T; p.A281V; 20:63490666-63490666	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.326C>T; p.A109V; 20:63495100-63495100	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.387G>T; p.K129N; 20:63495039-63495039	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.220G>T; p.D74Y; 20:63495960-63495960	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.220G>T; p.D74Y; 20:63495960-63495960	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.717G>A; p.T239T; 20:63493192-63493192	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.287G>A; p.R96H; 20:63495893-63495893	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.287G>A; p.R96H; 20:63495893-63495893	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.714_715insC; p.T239fs*50; 20:63493194-63493195	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1105G>A; p.A369T; 20:63489077-63489077	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1337G>C; p.G446A; 20:63488353-63488353	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.300G>T; p.K100N; 20:63495880-63495880	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.225C>A; p.I75I; 20:63495955-63495955	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.667G>A; p.A223T; 20:63493242-63493242	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.270C>T; p.I90I; 20:63495910-63495910	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.739C>T; p.R247C; 20:63493170-63493170	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.289G>A; p.D97N; 20:63495891-63495891	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.909G>A; p.L303L; 20:63490599-63490599	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1050G>A; p.P350P; 20:63489132-63489132	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1308C>T; p.G436G; 20:63488382-63488382	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1012G>T; p.A338S; 20:63490496-63490496	liver	carcinoma	Substitution - Missense
c.1012G>T; p.A338S; 20:63490496-63490496	liver	carcinoma	Substitution - Missense
c.594T>C; p.G198G; 20:63494832-63494832	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.925G>A; p.G309S; 20:63490583-63490583	liver	carcinoma	Substitution - Missense
c.925G>A; p.G309S; 20:63490583-63490583	liver	carcinoma	Substitution - Missense
c.876G>A; p.V292V; 20:63490632-63490632	liver	carcinoma	Substitution - coding silent
c.934G>T; p.V312L; 20:63490574-63490574	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.982G>A; p.D328N; 20:63490526-63490526	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1253A>C; p.Y418S; 20:63488929-63488929	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1253A>C; p.Y418S; 20:63488929-63488929	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1253A>C; p.Y418S; 20:63488929-63488929	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1202T>C; p.I401T; 20:63488980-63488980	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.872C>T; p.S291L; 20:63490636-63490636	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.501C>T; p.Y167Y; 20:63494925-63494925	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.354G>T; p.A118A; 20:63495072-63495072	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.967G>T; p.G323C; 20:63490541-63490541	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.864G>T; p.E288D; 20:63490644-63490644	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1105G>A; p.A369T; 20:63489077-63489077	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.521T>C; p.V174A; 20:63494905-63494905	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.798G>T; p.R266R; 20:63490710-63490710	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.998C>A; p.P333Q; 20:63490510-63490510	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.591C>A; p.H197Q; 20:63494835-63494835	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.593G>T; p.G198V; 20:63494833-63494833	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.425C>T; p.T142M; 20:63495001-63495001	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.616C>G; p.P206A; 20:63494810-63494810	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.999G>A; p.P333P; 20:63490509-63490509	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.31G>C; p.V11L; 20:63497733-63497733	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.137C>T; p.A46V; 20:63497627-63497627	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1257G>A; p.P419P; 20:63488925-63488925	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1257G>A; p.P419P; 20:63488925-63488925	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.719G>A; p.R240H; 20:63493190-63493190	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.821C>G; p.P274R; 20:63490687-63490687	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.964C>T; p.R322W; 20:63490544-63490544	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.199C>T; p.R67C; 20:63495981-63495981	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.765G>T; p.K255N; 20:63493144-63493144	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1280G>A; p.R427H; 20:63488410-63488410	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.455T>C; p.V152A; 20:63494971-63494971	ovary	carcinoma; adenocarcinoma	Substitution - Missense
c.54C>T; p.S18S; 20:63497710-63497710	ovary	other; neoplasm	Substitution - coding silent
c.1273G>A; p.A425T; 20:63488417-63488417	pancreas	carcinoma	Substitution - Missense
c.374C>T; p.A125V; 20:63495052-63495052	pancreas	carcinoma	Substitution - Missense
c.401G>A; p.R134Q; 20:63495025-63495025	pancreas	carcinoma	Substitution - Missense
c.354G>A; p.A118A; 20:63495072-63495072	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.961C>T; p.R321W; 20:63490547-63490547	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1076C>T; p.P359L; 20:63489106-63489106	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.680C>T; p.S227F; 20:63493229-63493229	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1253A>C; p.Y418S; 20:63488929-63488929	skin	malignant_melanoma	Substitution - Missense
c.1129G>A; p.E377K; 20:63489053-63489053	skin	malignant_melanoma	Substitution - Missense
c.107A>T; p.K36I; 20:63497657-63497657	skin	malignant_melanoma	Substitution - Missense
c.1187C>T; p.S396F; 20:63488995-63488995	skin	malignant_melanoma	Substitution - Missense
c.435G>A; p.V145V; 20:63494991-63494991	skin	malignant_melanoma	Substitution - coding silent
c.155G>A; p.G52E; 20:63496025-63496025	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1029G>A; p.Q343Q; 20:63490479-63490479	skin	malignant_melanoma	Substitution - coding silent
c.154G>A; p.G52R; 20:63496026-63496026	skin	malignant_melanoma	Substitution - Missense
c.154G>A; p.G52R; 20:63496026-63496026	skin	malignant_melanoma	Substitution - Missense
c.783G>A; p.T261T; 20:63490725-63490725	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.500A>T; p.Y167F; 20:63494926-63494926	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.828G>A; p.M276I; 20:63490680-63490680	skin	malignant_melanoma	Substitution - Missense
c.618C>T; p.P206P; 20:63494808-63494808	skin	malignant_melanoma	Substitution - coding silent
c.238T>C; p.F80L; 20:63495942-63495942	skin	malignant_melanoma	Substitution - Missense
c.1074C>A; p.S358S; 20:63489108-63489108	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1006G>A; p.E336K; 20:63490502-63490502	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.369C>T; p.F123F; 20:63495057-63495057	skin	malignant_melanoma	Substitution - coding silent
c.621+2T>G; p.?; 20:63494803-63494803	skin	malignant_melanoma	Unknown
c.1076C>T; p.P359L; 20:63489106-63489106	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.901G>A; p.E301K; 20:63490607-63490607	skin	malignant_melanoma	Substitution - Missense
c.901G>A; p.E301K; 20:63490607-63490607	skin	malignant_melanoma	Substitution - Missense
c.955G>A; p.D319N; 20:63490553-63490553	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.199C>T; p.R67C; 20:63495981-63495981	skin	malignant_melanoma	Substitution - Missense
c.456G>A; p.V152V; 20:63494970-63494970	skin	malignant_melanoma	Substitution - coding silent
c.280G>C; p.G94R; 20:63495900-63495900	skin	malignant_melanoma	Substitution - Missense
c.447C>T; p.I149I; 20:63494979-63494979	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.390T>C; p.N130N; 20:63495036-63495036	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.32T>C; p.V11A; 20:63497732-63497732	stomach	adenocarcinoma	Substitution - Missense
c.454G>A; p.V152M; 20:63494972-63494972	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.997C>A; p.P333T; 20:63490511-63490511	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.207C>T; p.R69R; 20:63495973-63495973	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.962G>A; p.R321Q; 20:63490546-63490546	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.387G>A; p.K129K; 20:63495039-63495039	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.434T>C; p.V145A; 20:63494992-63494992	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.448G>A; p.V150M; 20:63494978-63494978	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.188T>C; p.L63P; 20:63495992-63495992	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.353C>T; p.A118V; 20:63495073-63495073	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.594T>C; p.G198G; 20:63494832-63494832	thyroid	other; neoplasm	Substitution - coding silent
c.995A>C; p.D332A; 20:63490513-63490513	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.995A>C; p.D332A; 20:63490513-63490513	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.995A>C; p.D332A; 20:63490513-63490513	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.995A>C; p.D332A; 20:63490513-63490513	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.995A>C; p.D332A; 20:63490513-63490513	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.995A>C; p.D332A; 20:63490513-63490513	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.995A>C; p.D332A; 20:63490513-63490513	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.995A>C; p.D332A; 20:63490513-63490513	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.995A>C; p.D332A; 20:63490513-63490513	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.995A>C; p.D332A; 20:63490513-63490513	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1253A>C; p.Y418S; 20:63488929-63488929	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1253A>C; p.Y418S; 20:63488929-63488929	urinary_tract; bladder	carcinoma	Substitution - Missense
c.889G>A; p.E297K; 20:63490619-63490619	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1218G>T; p.P406P; 20:63488964-63488964	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.202G>C; p.E68Q; 20:63495978-63495978	urinary_tract; bladder	carcinoma	Substitution - Missense

Oncogene database

COSMIC confirmed somatic mutation [Top]

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