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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

1656

Name

DDX6

Synonymous

DEAD (Asp-Glu-Ala-Asp) box helicase 6;DDX6;DEAD (Asp-Glu-Ala-Asp) box helicase 6

Definition

ATP-dependent RNA helicase p54|DEAD (Asp-Glu-Ala-Asp) box polypeptide 6|DEAD box protein 6|DEAD box-6|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6 (RNA helicase, 54kD)|oncogene RCK|probable ATP-dependent RNA helicase DDX6

Position

11q23.3

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.231+6T>G; p.?; 11:118781115-118781115

 biliary_tract; gallbladdercarcinoma; adenocarcinomaUnknown

c.919G>A; p.E307K; 11:118758815-118758815

 breastcarcinomaSubstitution - Missense

c.1071G>C; p.M357I; 11:118757177-118757177

 breastcarcinomaSubstitution - Missense

c.1165A>T; p.I389L; 11:118755480-118755480

 breastcarcinomaSubstitution - Missense

c.1157G>T; p.G386V; 11:118755488-118755488

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.1157G>A; p.G386D; 11:118755488-118755488

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1157G>A; p.G386D; 11:118755488-118755488

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.490G>T; p.E164*; 11:118765332-118765332

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.543A>G; p.G181G; 11:118765279-118765279

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.873G>T; p.E291D; 11:118758861-118758861

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1294C>T; p.R432C; 11:118754837-118754837

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1368C>T; p.S456S; 11:118754763-118754763

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1085G>A; p.R362Q; 11:118756316-118756316

 endometriumcarcinoma; serous_carcinomaSubstitution - Missense

c.1144C>A; p.L382M; 11:118755501-118755501

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.764C>T; p.T255M; 11:118759989-118759989

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.764C>T; p.T255M; 11:118759989-118759989

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.1338T>A; p.I446I; 11:118754793-118754793

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.955T>A; p.S319T; 11:118758779-118758779

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.30G>A; p.L10L; 11:118786189-118786189

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.397A>G; p.T133A; 11:118768292-118768292

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.422T>G; p.I141S; 11:118768267-118768267

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.111C>A; p.T37T; 11:118786108-118786108

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.336G>A; p.Q112Q; 11:118779632-118779632

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.683A>G; p.H228R; 11:118763237-118763237

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1004G>A; p.R335Q; 11:118757244-118757244

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1126A>G; p.N376D; 11:118756275-118756275

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1170A>C; p.Q390H; 11:118755475-118755475

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.198delA; p.K66fs*7; 11:118781154-118781154

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.107delA; p.N36fs*16; 11:118786112-118786112

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.1184T>C; p.V395A; 11:118755461-118755461

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1184T>C; p.V395A; 11:118755461-118755461

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1085G>A; p.R362Q; 11:118756316-118756316

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1068A>G; p.K356K; 11:118757180-118757180

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1068A>G; p.K356K; 11:118757180-118757180

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.466+1G>T; p.?; 11:118768222-118768222

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.64G>T; p.G22*; 11:118786155-118786155

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.690G>T; p.Q230H; 11:118763230-118763230

 livercarcinomaSubstitution - Missense

c.650A>G; p.D217G; 11:118763270-118763270

 livercarcinomaSubstitution - Missense

c.562A>T; p.T188S; 11:118765260-118765260

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.279A>G; p.K93K; 11:118779689-118779689

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.436C>T; p.R146W; 11:118768253-118768253

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.78G>A; p.Q26Q; 11:118786141-118786141

 NSNSSubstitution - coding silent

c.1142-4delT; p.?; 11:118755507-118755507

 NSmalignant_melanomaUnknown

c.1066A>G; p.K356E; 11:118757182-118757182

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.832-3delC; p.?; 11:118758905-118758905

 pancreascarcinoma; acinar_carcinomaUnknown

c.782A>C; p.Q261P; 11:118759971-118759971

 prostatecarcinomaSubstitution - Missense

c.548C>A; p.A183D; 11:118765274-118765274

 skinmalignant_melanomaSubstitution - Missense

c.1144C>T; p.L382L; 11:118755501-118755501

 skinmalignant_melanomaSubstitution - coding silent

c.954C>T; p.F318F; 11:118758780-118758780

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.230C>T; p.S77L; 11:118781122-118781122

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.232-6G>T; p.?; 11:118779742-118779742

 soft_tissue; striated_musclerhabdomyosarcoma; embryonalUnknown

c.1142-4delT; p.?; 11:118755507-118755507

 stomachcarcinoma; diffuse_adenocarcinomaUnknown

c.1353C>T; p.S451S; 11:118754778-118754778

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.720G>C; p.L240F; 11:118760033-118760033

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1328G>A; p.G443E; 11:118754803-118754803

 urinary_tract; bladdercarcinomaSubstitution - Missense