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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

1649

Name

DDIT3

Synonymous

DNA-damage-inducible transcript 3;DDIT3;DNA-damage-inducible transcript 3

Definition

C/EBP zeta|CCAAT/enhancer-binding protein homologous protein|DDIT-3|DNA damage-inducible transcript 3 protein|c/EBP-homologous protein 10|growth arrest and DNA damage-inducible protein GADD153

Position

12q13.1-q13.2

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.277G>A; p.E93K; 12:57517042-57517042

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.58G>A; p.A20T; 12:57517349-57517349

 central_nervous_system; braingliomaSubstitution - Missense

c.343G>A; p.A115T; 12:57516976-57516976

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.94G>T; p.D32Y; 12:57517313-57517313

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.94G>T; p.D32Y; 12:57517313-57517313

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.340C>T; p.R114W; 12:57516979-57516979

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.440G>A; p.R147H; 12:57516879-57516879

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.435C>T; p.I145I; 12:57516884-57516884

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.65A>G; p.Y22C; 12:57517342-57517342

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.30C>T; p.F10F; 12:57517377-57517377

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.345T>C; p.A115A; 12:57516974-57516974

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.252T>C; p.D84D; 12:57517067-57517067

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.461C>T; p.A154V; 12:57516858-57516858

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.323G>C; p.S108T; 12:57516996-57516996

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.74T>C; p.L25P; 12:57517333-57517333

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.76C>T; p.Q26*; 12:57517331-57517331

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.419G>A; p.R140Q; 12:57516900-57516900

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.345T>C; p.A115A; 12:57516974-57516974

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.344C>T; p.A115V; 12:57516975-57516975

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.342G>A; p.R114R; 12:57516977-57516977

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.314_323del10; p.R105fs*13; 12:57516996-57517005

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.107delG; p.G36fs*28; 12:57517300-57517300

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.105G>T; p.G35G; 12:57517302-57517302

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.94G>T; p.D32Y; 12:57517313-57517313

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.20C>T; p.P7L; 12:57517387-57517387

 livercarcinomaSubstitution - Missense

c.20C>T; p.P7L; 12:57517387-57517387

 livercarcinomaSubstitution - Missense

c.361A>G; p.K121E; 12:57516958-57516958

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.387G>C; p.R129S; 12:57516932-57516932

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.387G>A; p.R129R; 12:57516932-57516932

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.10G>A; p.E4K; 12:57517397-57517397

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.419G>T; p.R140L; 12:57516900-57516900

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.74T>G; p.L25R; 12:57517333-57517333

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.343G>A; p.A115T; 12:57516976-57516976

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.361A>C; p.K121Q; 12:57516958-57516958

 prostatecarcinomaSubstitution - Missense

c.467G>T; p.R156L; 12:57516852-57516852

 prostatecarcinomaSubstitution - Missense

c.104G>A; p.G35E; 12:57517303-57517303

 skinmalignant_melanomaSubstitution - Missense

c.85C>T; p.L29L; 12:57517322-57517322

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.28T>G; p.F10V; 12:57517379-57517379

 skinmalignant_melanomaSubstitution - Missense

c.15A>C; p.S5S; 12:57517392-57517392

 skinmalignant_melanomaSubstitution - coding silent

c.128G>A; p.G43E; 12:57517279-57517279

 skinmalignant_melanomaSubstitution - Missense

c.122C>T; p.P41L; 12:57517285-57517285

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.442C>T; p.L148L; 12:57516877-57516877

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.416A>G; p.E139G; 12:57516903-57516903

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.195G>T; p.E65D; 12:57517124-57517124

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.440G>A; p.R147H; 12:57516879-57516879

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.109A>G; p.T37A; 12:57517298-57517298

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.193G>A; p.E65K; 12:57517126-57517126

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.193G>A; p.E65K; 12:57517126-57517126

 urinary_tract; bladdercarcinomaSubstitution - Missense