Entrez Gene

Basic Information
Gene ID	151871
Name	DPPA2
Synonymous	developmental pluripotency associated 2;DPPA2;developmental pluripotency associated 2
Definition	cancer/testis antigen 100\|developmental pluripotency-associated protein 2\|embryonic stem cell (ESC) associated transcript 15-2\|pluripotent embryonic stem cell-related gene 1 protein
Position	3q13.13
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC confirmed somatic mutation [Top]

c.118A>T; p.M40L; 3:109312608-109312608	bone	osteosarcoma	Substitution - Missense
c.441G>C; p.S147S; 3:109308249-109308249	breast	carcinoma	Substitution - coding silent
c.814G>A; p.G272S; 3:109304515-109304515	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.102C>T; p.D34D; 3:109312624-109312624	breast	carcinoma	Substitution - coding silent
c.577G>A; p.A193T; 3:109308113-109308113	breast	carcinoma	Substitution - Missense
c.656C>T; p.S219F; 3:109308034-109308034	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.282G>C; p.K94N; 3:109309230-109309230	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.274A>G; p.I92V; 3:109309238-109309238	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.468_469delAG; p.R156fs*8; 3:109308221-109308222	endometrium	carcinoma; endometrioid_carcinoma	Deletion - Frameshift
c.258G>A; p.P86P; 3:109309254-109309254	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.550G>A; p.A184T; 3:109308140-109308140	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.550G>A; p.A184T; 3:109308140-109308140	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.330T>G; p.S110R; 3:109309182-109309182	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.767G>A; p.R256K; 3:109304562-109304562	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.705A>G; p.T235T; 3:109304624-109304624	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.54A>G; p.V18V; 3:109312672-109312672	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.599A>G; p.K200R; 3:109308091-109308091	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.599A>G; p.K200R; 3:109308091-109308091	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.809C>T; p.S270F; 3:109304520-109304520	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.197C>A; p.T66K; 3:109309315-109309315	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.333T>C; p.T111T; 3:109309179-109309179	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.440C>T; p.S147L; 3:109308250-109308250	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.102C>T; p.D34D; 3:109312624-109312624	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.661G>A; p.V221I; 3:109304668-109304668	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.446A>T; p.K149I; 3:109308244-109308244	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.410T>C; p.M137T; 3:109308280-109308280	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.94A>G; p.K32E; 3:109312632-109312632	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.181G>T; p.G61C; 3:109312545-109312545	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.660C>T; p.G220G; 3:109304669-109304669	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.39C>A; p.F13L; 3:109312687-109312687	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.39C>A; p.F13L; 3:109312687-109312687	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.392G>A; p.R131Q; 3:109309030-109309030	liver	carcinoma	Substitution - Missense
c.545C>T; p.P182L; 3:109308145-109308145	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.590T>C; p.V197A; 3:109308100-109308100	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.840C>A; p.P280P; 3:109304489-109304489	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.673G>C; p.V225L; 3:109304656-109304656	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.281A>T; p.K94M; 3:109309231-109309231	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.723G>T; p.L241L; 3:109304606-109304606	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.376G>T; p.A126S; 3:109309046-109309046	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.563C>A; p.S188*; 3:109308127-109308127	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.12A>T; p.A4A; 3:109314531-109314531	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.348C>T; p.I116I; 3:109309074-109309074	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.747G>A; p.W249*; 3:109304582-109304582	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.102C>T; p.D34D; 3:109312624-109312624	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.819A>G; p.I273M; 3:109304510-109304510	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.112G>A; p.E38K; 3:109312614-109312614	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.433C>T; p.R145*; 3:109308257-109308257	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.719G>A; p.R240H; 3:109304610-109304610	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.765G>T; p.R255S; 3:109304564-109304564	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.474G>C; p.R158S; 3:109308216-109308216	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.614G>T; p.C205F; 3:109308076-109308076	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.624T>G; p.P208P; 3:109308066-109308066	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.513G>C; p.E171D; 3:109308177-109308177	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.43G>A; p.E15K; 3:109312683-109312683	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.33+1G>T; p.?; 3:109314509-109314509	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.242C>T; p.P81L; 3:109309270-109309270	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.181G>T; p.G61C; 3:109312545-109312545	lung	carcinoma; large_cell_carcinoma	Substitution - Missense
c.234C>A; p.C78*; 3:109309278-109309278	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.886G>A; p.V296I; 3:109300404-109300404	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.591T>A; p.V197V; 3:109308099-109308099	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.92T>G; p.V31G; 3:109312634-109312634	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.191T>C; p.L64P; 3:109309321-109309321	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.29A>G; p.K10R; 3:109314514-109314514	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.600G>A; p.K200K; 3:109308090-109308090	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.434G>A; p.R145Q; 3:109308256-109308256	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.202G>A; p.E68K; 3:109309310-109309310	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.202G>A; p.E68K; 3:109309310-109309310	skin	malignant_melanoma	Substitution - Missense
c.679C>A; p.H227N; 3:109304650-109304650	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.839C>T; p.P280L; 3:109304490-109304490	skin	malignant_melanoma	Substitution - Missense
c.250_251CC>TT; p.P84>?; 3:109309261-109309262	skin; trunk	malignant_melanoma	Complex
c.804C>T; p.F268F; 3:109304525-109304525	skin	malignant_melanoma	Substitution - coding silent
c.767G>A; p.R256K; 3:109304562-109304562	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.134C>T; p.S45F; 3:109312592-109312592	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.852G>A; p.K284K; 3:109304477-109304477	skin	malignant_melanoma	Substitution - coding silent
c.440C>T; p.S147L; 3:109308250-109308250	skin	malignant_melanoma	Substitution - Missense
c.434G>A; p.R145Q; 3:109308256-109308256	skin; upper_leg	malignant_melanoma	Substitution - Missense
c.348C>T; p.I116I; 3:109309074-109309074	skin	malignant_melanoma	Substitution - coding silent
c.709G>A; p.G237S; 3:109304620-109304620	skin	malignant_melanoma	Substitution - Missense
c.39C>T; p.F13F; 3:109312687-109312687	skin	malignant_melanoma	Substitution - coding silent
c.89C>T; p.P30L; 3:109312637-109312637	skin	malignant_melanoma	Substitution - Missense
c.730C>T; p.H244Y; 3:109304599-109304599	skin; leg	malignant_melanoma	Substitution - Missense
c.730C>T; p.H244Y; 3:109304599-109304599	skin; leg	malignant_melanoma	Substitution - Missense
c.730C>T; p.H244Y; 3:109304599-109304599	skin	malignant_melanoma	Substitution - Missense
c.611C>T; p.S204L; 3:109308079-109308079	skin	malignant_melanoma	Substitution - Missense
c.102C>T; p.D34D; 3:109312624-109312624	skin	malignant_melanoma	Substitution - coding silent
c.184C>T; p.H62Y; 3:109309328-109309328	skin	malignant_melanoma	Substitution - Missense
c.855G>A; p.R285R; 3:109300435-109300435	skin	malignant_melanoma	Substitution - coding silent
c.224A>C; p.K75T; 3:109309288-109309288	skin	malignant_melanoma	Substitution - Missense
c.120G>A; p.M40I; 3:109312606-109312606	skin	malignant_melanoma	Substitution - Missense
c.120G>A; p.M40I; 3:109312606-109312606	skin	malignant_melanoma	Substitution - Missense
c.120G>A; p.M40I; 3:109312606-109312606	skin	malignant_melanoma	Substitution - Missense
c.343-1G>A; p.?; 3:109309080-109309080	skin	malignant_melanoma	Unknown
c.343-1G>A; p.?; 3:109309080-109309080	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.739C>T; p.Q247*; 3:109304590-109304590	skin	malignant_melanoma	Substitution - Nonsense
c.322G>T; p.G108C; 3:109309190-109309190	skin	malignant_melanoma	Substitution - Missense
c.691C>T; p.L231F; 3:109304638-109304638	skin	malignant_melanoma	Substitution - Missense
c.877T>A; p.L293I; 3:109300413-109300413	skin	malignant_melanoma	Substitution - Missense
c.49G>A; p.E17K; 3:109312677-109312677	skin	malignant_melanoma	Substitution - Missense
c.49G>A; p.E17K; 3:109312677-109312677	skin	malignant_melanoma	Substitution - Missense
c.49G>A; p.E17K; 3:109312677-109312677	skin	malignant_melanoma	Substitution - Missense
c.49G>A; p.E17K; 3:109312677-109312677	skin	malignant_melanoma	Substitution - Missense
c.251C>T; p.P84L; 3:109309261-109309261	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.251C>T; p.P84L; 3:109309261-109309261	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.204G>A; p.E68E; 3:109309308-109309308	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.19G>T; p.D7Y; 3:109314524-109314524	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.716T>C; p.V239A; 3:109304613-109304613	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.371G>T; p.R124M; 3:109309051-109309051	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.448C>T; p.R150C; 3:109308242-109308242	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.734C>T; p.A245V; 3:109304595-109304595	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.331A>G; p.T111A; 3:109309181-109309181	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.187C>A; p.L63I; 3:109309325-109309325	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.261C>A; p.T87T; 3:109309251-109309251	thyroid	other; neoplasm	Substitution - coding silent
c.205C>T; p.Q69*; 3:109309307-109309307	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.864G>C; p.K288N; 3:109300426-109300426	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.168G>A; p.K56K; 3:109312558-109312558	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.439T>G; p.S147A; 3:109308251-109308251	urinary_tract; bladder	carcinoma	Substitution - Missense

Oncogene database

COSMIC confirmed somatic mutation [Top]

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