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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

1398

Name

CRK

Synonymous

v-crk avian sarcoma virus CT10 oncogene homolog;CRK;v-crk avian sarcoma virus CT10 oncogene homolog

Definition

adapter molecule crk|proto-oncogene c-Crk

Position

17p13.3

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.401C>T; p.A134V; 17:1436996-1436996

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.485G>A; p.R162Q; 17:1436912-1436912

 breastcarcinomaSubstitution - Missense

c.854A>G; p.H285R; 17:1423574-1423574

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.853C>A; p.H285N; 17:1423575-1423575

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.856T>A; p.F286I; 17:1423572-1423572

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.855C>T; p.H285H; 17:1423573-1423573

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.850G>A; p.G284S; 17:1423578-1423578

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.852T>C; p.G284G; 17:1423576-1423576

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.346G>T; p.E116*; 17:1437051-1437051

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.686C>T; p.P229L; 17:1436711-1436711

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.807T>C; p.I269I; 17:1423621-1423621

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.296C>T; p.A99V; 17:1437101-1437101

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.558C>T; p.Y186Y; 17:1436839-1436839

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.73G>A; p.A25T; 17:1456045-1456045

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.49A>C; p.R17R; 17:1456069-1456069

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.49A>C; p.R17R; 17:1456069-1456069

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.49A>C; p.R17R; 17:1456069-1456069

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.49A>C; p.R17R; 17:1456069-1456069

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.49A>C; p.R17R; 17:1456069-1456069

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.49A>C; p.R17R; 17:1456069-1456069

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.49A>C; p.R17R; 17:1456069-1456069

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.49A>C; p.R17R; 17:1456069-1456069

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.583G>A; p.A195T; 17:1436814-1436814

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.660C>A; p.P220P; 17:1436737-1436737

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.6G>A; p.A2A; 17:1456112-1456112

 livercarcinomaSubstitution - coding silent

c.6G>A; p.A2A; 17:1456112-1456112

 livercarcinomaSubstitution - coding silent

c.6G>A; p.A2A; 17:1456112-1456112

 livercarcinoma; hepatocellular_carcinomaSubstitution - coding silent

c.373A>G; p.S125G; 17:1437024-1437024

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.84G>T; p.Q28H; 17:1456034-1456034

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.481A>T; p.I161F; 17:1436916-1436916

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.369G>C; p.Q123H; 17:1437028-1437028

 lungcarcinoma; non_small_cell_carcinomaSubstitution - Missense

c.420C>G; p.L140L; 17:1436977-1436977

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.259C>G; p.L87V; 17:1437138-1437138

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.15C>G; p.F5L; 17:1456103-1456103

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.646C>T; p.P216S; 17:1436751-1436751

 prostatecarcinomaSubstitution - Missense

c.172T>G; p.S58A; 17:1455946-1455946

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.718G>T; p.A240S; 17:1436679-1436679

 skinmalignant_melanomaSubstitution - Missense

c.553C>T; p.P185S; 17:1436844-1436844

 skinmalignant_melanomaSubstitution - Missense

c.456C>G; p.P152P; 17:1436941-1436941

 skinmalignant_melanomaSubstitution - coding silent

c.685C>T; p.P229S; 17:1436712-1436712

 skinmalignant_melanomaSubstitution - Missense

c.494C>T; p.P165L; 17:1436903-1436903

 skinmalignant_melanomaSubstitution - Missense

c.362C>T; p.S121F; 17:1437035-1437035

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.782G>T; p.G261V; 17:1423646-1423646

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.431A>T; p.N144I; 17:1436966-1436966

 skinmalignant_melanomaSubstitution - Missense

c.691C>T; p.P231S; 17:1436706-1436706

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.242-4_242-3insT; p.?; 17:1437158-1437159

 stomachadenocarcinomaUnknown

c.883G>C; p.D295H; 17:1423545-1423545

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.49A>C; p.R17R; 17:1456069-1456069

 thyroidother; neoplasmSubstitution - coding silent

c.49A>C; p.R17R; 17:1456069-1456069

 thyroidother; neoplasmSubstitution - coding silent

c.49A>C; p.R17R; 17:1456069-1456069

 thyroidother; neoplasmSubstitution - coding silent

c.49A>C; p.R17R; 17:1456069-1456069

 thyroidother; neoplasmSubstitution - coding silent

c.466G>A; p.G156R; 17:1436931-1436931

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense