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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

10987

Name

COPS5

Synonymous

COP9 signalosome subunit 5;COPS5;COP9 signalosome subunit 5

Definition

38 kDa Mov34 homolog|COP9 constitutive photomorphogenic homolog subunit 5|COP9 signalosome complex subunit 5|jun activation domain-binding protein 1|signalosome subunit 5

Position

8q13.1

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.142G>A; p.D48N; 8:67061855-67061855

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.649C>T; p.H217Y; 8:67056529-67056529

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.583C>A; p.P195T; 8:67056595-67056595

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.181G>A; p.A61T; 8:67059408-67059408

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.402C>T; p.I134I; 8:67058188-67058188

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.34A>G; p.T12A; 8:67061963-67061963

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.179T>C; p.L60S; 8:67059410-67059410

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.804T>A; p.D268E; 8:67045928-67045928

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.441T>C; p.L147L; 8:67058149-67058149

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.531C>T; p.S177S; 8:67057422-67057422

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.212C>T; p.S71L; 8:67059377-67059377

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.710T>A; p.L237*; 8:67051291-67051291

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.838C>T; p.L280L; 8:67045894-67045894

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.353C>T; p.A118V; 8:67059236-67059236

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.756T>G; p.S252S; 8:67051245-67051245

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.465G>T; p.Q155H; 8:67058125-67058125

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.695C>G; p.S232C; 8:67051306-67051306

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.881G>A; p.R294Q; 8:67045851-67045851

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.872C>T; p.T291M; 8:67045860-67045860

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.494T>G; p.F165C; 8:67058096-67058096

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.494T>G; p.F165C; 8:67058096-67058096

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.667G>T; p.A223S; 8:67051334-67051334

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.235G>A; p.G79S; 8:67059354-67059354

 livercarcinomaSubstitution - Missense

c.991A>G; p.I331V; 8:67043247-67043247

 livercarcinomaSubstitution - Missense

c.991A>G; p.I331V; 8:67043247-67043247

 livercarcinomaSubstitution - Missense

c.934A>G; p.I312V; 8:67043304-67043304

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.488A>G; p.E163G; 8:67058102-67058102

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.213G>C; p.S71S; 8:67059376-67059376

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.499G>A; p.A167T; 8:67058091-67058091

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.22A>G; p.M8V; 8:67061975-67061975

 lung; middle_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.403G>T; p.G135W; 8:67058187-67058187

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.816G>T; p.K272N; 8:67045916-67045916

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.328C>G; p.Q110E; 8:67059261-67059261

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.61G>A; p.E21K; 8:67061936-67061936

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.26C>T; p.A9V; 8:67061971-67061971

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.126G>T; p.A42A; 8:67061871-67061871

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.832G>A; p.A278T; 8:67045900-67045900

 pleurapulmonary_blastomaSubstitution - Missense

c.809C>T; p.S270F; 8:67045923-67045923

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.531C>T; p.S177S; 8:67057422-67057422

 skinmalignant_melanomaSubstitution - coding silent

c.512A>T; p.D171V; 8:67057441-67057441

 skinmalignant_melanomaSubstitution - Missense

c.912A>G; p.T304T; 8:67045820-67045820

 skinmalignant_melanomaSubstitution - coding silent

c.314C>T; p.T105I; 8:67059275-67059275

 skin; trunkmalignant_melanomaSubstitution - Missense

c.134G>A; p.W45*; 8:67061863-67061863

 skin; upper_legmalignant_melanomaSubstitution - Nonsense

c.703C>T; p.R235C; 8:67051298-67051298

 skinmalignant_melanomaSubstitution - Missense

c.703C>T; p.R235C; 8:67051298-67051298

 skinmalignant_melanomaSubstitution - Missense

c.574-1G>A; p.?; 8:67056605-67056605

 skinmalignant_melanomaUnknown

c.331G>A; p.A111T; 8:67059258-67059258

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.397G>T; p.A133S; 8:67058193-67058193

 skinmalignant_melanomaSubstitution - Missense

c.772-1G>A; p.?; 8:67045961-67045961

 skin; scalpcarcinoma; squamous_cell_carcinomaUnknown

c.226G>A; p.E76K; 8:67059363-67059363

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.251A>T; p.K84M; 8:67059338-67059338

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.419A>G; p.H140R; 8:67058171-67058171

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.34A>G; p.T12A; 8:67061963-67061963

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.747G>A; p.T249T; 8:67051254-67051254

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.680C>T; p.S227L; 8:67051321-67051321

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.680C>T; p.S227L; 8:67051321-67051321

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.126G>A; p.A42A; 8:67061871-67061871

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.126G>A; p.A42A; 8:67061871-67061871

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent