Entrez Gene

Basic Information
Gene ID	10863
Name	ADAM28
Synonymous	ADAM metallopeptidase domain 28;ADAM28;ADAM metallopeptidase domain 28
Definition	disintegrin and metalloproteinase domain-containing protein 28\|epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II\|epididymial metalloproteinase-like, disintegrin-like, and cysteine-rich protein II\|metalloproteinase-like, dis
Position	8p21.2
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC confirmed somatic mutation [Top]

c.1808G>T; p.G603V; 8:24341735-24341735	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.33C>A; p.L11L; 8:24294182-24294182	autonomic_ganglia	neuroblastoma	Substitution - coding silent
c.1050C>T; p.D350D; 8:24330062-24330062	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - coding silent
c.149A>G; p.Q50R; 8:24300076-24300076	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.866G>A; p.R289H; 8:24323979-24323979	bone; extraskeletal	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1704T>G; p.G568G; 8:24341631-24341631	breast	carcinoma	Substitution - coding silent
c.1976C>G; p.S659C; 8:24343570-24343570	breast	carcinoma	Substitution - Missense
c.1048G>A; p.D350N; 8:24330060-24330060	breast	carcinoma	Substitution - Missense
c.1018G>C; p.E340Q; 8:24330030-24330030	breast	carcinoma	Substitution - Missense
c.2206G>T; p.D736Y; 8:24352014-24352014	breast	carcinoma	Substitution - Missense
c.890+1G>A; p.?; 8:24324004-24324004	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Unknown
c.890+1G>A; p.?; 8:24324004-24324004	central_nervous_system; brain	glioma	Unknown
c.694T>C; p.F232L; 8:24321263-24321263	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1050C>T; p.D350D; 8:24330062-24330062	central_nervous_system; brain	glioma	Substitution - coding silent
c.792G>A; p.K264K; 8:24323905-24323905	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.2060G>A; p.R687Q; 8:24349933-24349933	central_nervous_system; brain	glioma	Substitution - Missense
c.1821C>T; p.G607G; 8:24341748-24341748	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1950A>G; p.G650G; 8:24343544-24343544	central_nervous_system; brain	glioma	Substitution - coding silent
c.1416C>T; p.C472C; 8:24335490-24335490	central_nervous_system; brain	glioma	Substitution - coding silent
c.1899C>A; p.C633*; 8:24343169-24343169	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Nonsense
c.1899C>A; p.C633*; 8:24343169-24343169	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Nonsense
c.16C>G; p.L6V; 8:24294165-24294165	central_nervous_system; brain	glioma	Substitution - Missense
c.963C>T; p.G321G; 8:24326626-24326626	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.217delA; p.N75fs*53; 8:24309960-24309960	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Deletion - Frameshift
c.1734G>T; p.R578R; 8:24341661-24341661	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1734G>T; p.R578R; 8:24341661-24341661	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1853T>C; p.V618A; 8:24343123-24343123	central_nervous_system; brain	glioma	Substitution - Missense
c.535G>A; p.D179N; 8:24313539-24313539	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1682G>T; p.C561F; 8:24341609-24341609	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.822G>T; p.E274D; 8:24323935-24323935	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1756A>T; p.K586*; 8:24341683-24341683	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.260A>C; p.Y87S; 8:24310195-24310195	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.703G>T; p.A235S; 8:24321272-24321272	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.252G>A; p.T84T; 8:24310187-24310187	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.325G>T; p.G109*; 8:24311379-24311379	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1830G>T; p.K610N; 8:24341757-24341757	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1800G>T; p.V600V; 8:24341727-24341727	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.506G>A; p.C169Y; 8:24313510-24313510	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.312T>G; p.D104E; 8:24311366-24311366	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1299C>T; p.C433C; 8:24332677-24332677	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1953G>T; p.W651C; 8:24343547-24343547	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.534C>T; p.H178H; 8:24313538-24313538	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1281+4T>C; p.?; 8:24331331-24331331	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.1778C>A; p.T593K; 8:24341705-24341705	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.383+1G>A; p.?; 8:24311438-24311438	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.2052G>A; p.M684I; 8:24349925-24349925	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1409A>T; p.D470V; 8:24335483-24335483	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2199T>C; p.H733H; 8:24352007-24352007	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.433C>T; p.P145S; 8:24313437-24313437	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.160G>T; p.E54*; 8:24309903-24309903	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.534C>T; p.H178H; 8:24313538-24313538	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2266delC; p.P757fs*>19; 8:24353791-24353791	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.535G>A; p.D179N; 8:24313539-24313539	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.806C>T; p.A269V; 8:24323919-24323919	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1734G>C; p.R578R; 8:24341661-24341661	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.892G>A; p.A298T; 8:24326555-24326555	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.822G>T; p.E274D; 8:24323935-24323935	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.822G>T; p.E274D; 8:24323935-24323935	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1409A>G; p.D470G; 8:24335483-24335483	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1409A>G; p.D470G; 8:24335483-24335483	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1409A>G; p.D470G; 8:24335483-24335483	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1409A>G; p.D470G; 8:24335483-24335483	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1409A>G; p.D470G; 8:24335483-24335483	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.287C>G; p.T96S; 8:24310222-24310222	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1319A>G; p.K440R; 8:24332697-24332697	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.866G>A; p.R289H; 8:24323979-24323979	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1733G>T; p.R578L; 8:24341660-24341660	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1733G>A; p.R578Q; 8:24341660-24341660	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1733G>A; p.R578Q; 8:24341660-24341660	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1733G>A; p.R578Q; 8:24341660-24341660	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1733G>A; p.R578Q; 8:24341660-24341660	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.586G>T; p.D196Y; 8:24320245-24320245	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1990C>T; p.H664Y; 8:24343584-24343584	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1497C>T; p.H499H; 8:24335571-24335571	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1423C>T; p.P475S; 8:24335497-24335497	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2059C>T; p.R687W; 8:24349932-24349932	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1100T>A; p.L367Q; 8:24330112-24330112	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1710G>A; p.S570S; 8:24341637-24341637	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1356T>A; p.C452*; 8:24332734-24332734	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.961G>C; p.G321R; 8:24326624-24326624	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.426T>G; p.P142P; 8:24313430-24313430	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1778C>A; p.T593K; 8:24341705-24341705	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1154A>G; p.K385R; 8:24331200-24331200	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.210T>C; p.L70L; 8:24309953-24309953	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.104G>T; p.R35I; 8:24300031-24300031	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1685G>A; p.G562E; 8:24341612-24341612	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.964G>A; p.V322I; 8:24326627-24326627	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.723T>G; p.L241L; 8:24323836-24323836	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2027C>T; p.A676V; 8:24349900-24349900	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.216G>A; p.L72L; 8:24309959-24309959	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.350C>A; p.S117Y; 8:24311404-24311404	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1732C>T; p.R578W; 8:24341659-24341659	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1732C>T; p.R578W; 8:24341659-24341659	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.201T>C; p.I67I; 8:24309944-24309944	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1420C>T; p.L474L; 8:24335494-24335494	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1420C>T; p.L474L; 8:24335494-24335494	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.301A>T; p.I101F; 8:24310236-24310236	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.431G>T; p.S144I; 8:24313435-24313435	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.982G>A; p.D328N; 8:24329994-24329994	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.981C>T; p.S327S; 8:24329993-24329993	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.217delA; p.N75fs*53; 8:24309960-24309960	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.217delA; p.N75fs*53; 8:24309960-24309960	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.217delA; p.N75fs*53; 8:24309960-24309960	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1375delA; p.K460fs*46; 8:24335449-24335449	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.216_217insA; p.N75fs*15; 8:24309959-24309960	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.216_217insA; p.N75fs*15; 8:24309959-24309960	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.216_217insA; p.N75fs*15; 8:24309959-24309960	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.216_217insA; p.N75fs*15; 8:24309959-24309960	large_intestine	carcinoma; adenocarcinoma	Insertion - Frameshift
c.216_217insA; p.N75fs*15; 8:24309959-24309960	large_intestine	carcinoma; adenocarcinoma	Insertion - Frameshift
c.216_217insA; p.N75fs*15; 8:24309959-24309960	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1822G>A; p.D608N; 8:24341749-24341749	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.216_217insA; p.N75fs*15; 8:24309959-24309960	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.216_217insA; p.N75fs*15; 8:24309959-24309960	large_intestine	carcinoma; adenocarcinoma	Insertion - Frameshift
c.216_217insA; p.N75fs*15; 8:24309959-24309960	large_intestine	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1288A>G; p.T430A; 8:24332666-24332666	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.473A>G; p.Y158C; 8:24313477-24313477	liver	carcinoma	Substitution - Missense
c.473A>G; p.Y158C; 8:24313477-24313477	liver	carcinoma	Substitution - Missense
c.354C>T; p.D118D; 8:24311408-24311408	liver	carcinoma	Substitution - coding silent
c.354C>T; p.D118D; 8:24311408-24311408	liver	carcinoma	Substitution - coding silent
c.1568-10C>T; p.?; 8:24339456-24339456	liver	carcinoma	Unknown
c.2308-5T>C; p.?; 8:24354379-24354379	liver	carcinoma; hepatocellular_carcinoma	Unknown
c.1223C>A; p.P408Q; 8:24331269-24331269	liver	carcinoma	Substitution - Missense
c.1223C>A; p.P408Q; 8:24331269-24331269	liver	carcinoma	Substitution - Missense
c.1706G>T; p.G569V; 8:24341633-24341633	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1960C>T; p.P654S; 8:24343554-24343554	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.368C>G; p.T123R; 8:24311422-24311422	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.898G>T; p.E300*; 8:24326561-24326561	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1719G>C; p.L573F; 8:24341646-24341646	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1667C>G; p.A556G; 8:24339565-24339565	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.478C>T; p.P160S; 8:24313482-24313482	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.375G>C; p.R125S; 8:24311429-24311429	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.662A>G; p.N221S; 8:24321231-24321231	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.967G>A; p.V323I; 8:24326630-24326630	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1734G>A; p.R578R; 8:24341661-24341661	lung	carcinoma; non_small_cell_carcinoma	Substitution - coding silent
c.1921C>T; p.H641Y; 8:24343515-24343515	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1481G>T; p.G494V; 8:24335555-24335555	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.393C>T; p.F131F; 8:24313397-24313397	NS	malignant_melanoma	Substitution - coding silent
c.393C>T; p.F131F; 8:24313397-24313397	NS	malignant_melanoma	Substitution - coding silent
c.2059C>T; p.R687W; 8:24349932-24349932	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1540G>A; p.E514K; 8:24335614-24335614	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2050A>C; p.M684L; 8:24349923-24349923	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.567C>A; p.T189T; 8:24313571-24313571	oesophagus	carcinoma	Substitution - coding silent
c.1139G>A; p.R380H; 8:24331185-24331185	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.722T>G; p.L241R; 8:24323835-24323835	oesophagus	carcinoma	Substitution - Missense
c.216_217insA; p.N75fs*15; 8:24309959-24309960	oesophagus; lower_third	carcinoma; adenocarcinoma	Insertion - Frameshift
c.2172C>A; p.P724P; 8:24351304-24351304	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1713T>A; p.D571E; 8:24341640-24341640	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.982G>A; p.D328N; 8:24329994-24329994	pituitary; craniopharyngeal_duct	craniopharyngioma; adamantinomatous	Substitution - Missense
c.1821C>T; p.G607G; 8:24341748-24341748	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.1709C>T; p.S570L; 8:24341636-24341636	skin	malignant_melanoma	Substitution - Missense
c.346G>A; p.V116I; 8:24311400-24311400	skin	malignant_melanoma	Substitution - Missense
c.2240C>T; p.S747F; 8:24352048-24352048	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.950C>T; p.P317L; 8:24326613-24326613	skin	malignant_melanoma	Substitution - Missense
c.857G>A; p.R286K; 8:24323970-24323970	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1408G>A; p.D470N; 8:24335482-24335482	skin	malignant_melanoma	Substitution - Missense
c.1045C>T; p.H349Y; 8:24330057-24330057	skin	malignant_melanoma	Substitution - Missense
c.1233G>A; p.G411G; 8:24331279-24331279	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1233G>A; p.G411G; 8:24331279-24331279	skin	malignant_melanoma	Substitution - coding silent
c.1233G>A; p.G411G; 8:24331279-24331279	skin	malignant_melanoma	Substitution - coding silent
c.1045C>T; p.H349Y; 8:24330057-24330057	skin	malignant_melanoma	Substitution - Missense
c.1233G>A; p.G411G; 8:24331279-24331279	skin	malignant_melanoma	Substitution - coding silent
c.1233G>A; p.G411G; 8:24331279-24331279	skin	malignant_melanoma	Substitution - coding silent
c.535G>A; p.D179N; 8:24313539-24313539	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1045C>T; p.H349Y; 8:24330057-24330057	skin; trunk	malignant_melanoma	Substitution - Missense
c.1503G>A; p.K501K; 8:24335577-24335577	skin	malignant_melanoma	Substitution - coding silent
c.753A>C; p.L251F; 8:24323866-24323866	skin; hand	malignant_melanoma	Substitution - Missense
c.1086G>A; p.V362V; 8:24330098-24330098	skin	malignant_melanoma	Substitution - coding silent
c.231C>T; p.N77N; 8:24310166-24310166	skin	malignant_melanoma	Substitution - coding silent
c.1018G>A; p.E340K; 8:24330030-24330030	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1018G>A; p.E340K; 8:24330030-24330030	skin	malignant_melanoma	Substitution - Missense
c.2230C>G; p.P744A; 8:24352038-24352038	skin	malignant_melanoma	Substitution - Missense
c.1018G>A; p.E340K; 8:24330030-24330030	skin	malignant_melanoma	Substitution - Missense
c.1018G>A; p.E340K; 8:24330030-24330030	skin	malignant_melanoma	Substitution - Missense
c.763G>A; p.E255K; 8:24323876-24323876	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.763G>A; p.E255K; 8:24323876-24323876	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.763G>A; p.E255K; 8:24323876-24323876	skin	malignant_melanoma	Substitution - Missense
c.414C>T; p.Y138Y; 8:24313418-24313418	skin	malignant_melanoma	Substitution - coding silent
c.1445C>T; p.S482F; 8:24335519-24335519	skin; upper_arm	malignant_melanoma	Substitution - Missense
c.1445C>T; p.S482F; 8:24335519-24335519	skin	malignant_melanoma	Substitution - Missense
c.639T>C; p.D213D; 8:24320298-24320298	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1349G>A; p.G450E; 8:24332727-24332727	skin; upper_leg	malignant_melanoma	Substitution - Missense
c.1861G>A; p.E621K; 8:24343131-24343131	skin	malignant_melanoma	Substitution - Missense
c.601G>A; p.E201K; 8:24320260-24320260	skin	malignant_melanoma	Substitution - Missense
c.448G>A; p.G150R; 8:24313452-24313452	skin	malignant_melanoma	Substitution - Missense
c.1505G>A; p.G502D; 8:24335579-24335579	skin	malignant_melanoma	Substitution - Missense
c.1746C>T; p.F582F; 8:24341673-24341673	skin	malignant_melanoma	Substitution - coding silent
c.1481G>A; p.G494D; 8:24335555-24335555	skin	malignant_melanoma	Substitution - Missense
c.1746C>T; p.F582F; 8:24341673-24341673	skin	malignant_melanoma	Substitution - coding silent
c.1729G>A; p.G577R; 8:24341656-24341656	skin	malignant_melanoma	Substitution - Missense
c.393C>T; p.F131F; 8:24313397-24313397	skin	malignant_melanoma	Substitution - coding silent
c.183G>A; p.M61I; 8:24309926-24309926	skin	malignant_melanoma	Substitution - Missense
c.2073C>A; p.S691S; 8:24349946-24349946	skin	malignant_melanoma	Substitution - coding silent
c.1568-1G>A; p.?; 8:24339465-24339465	skin	malignant_melanoma	Unknown
c.1957C>T; p.P653S; 8:24343551-24343551	skin	malignant_melanoma	Substitution - Missense
c.1141C>G; p.L381V; 8:24331187-24331187	skin	malignant_melanoma	Substitution - Missense
c.194G>A; p.G65E; 8:24309937-24309937	skin	malignant_melanoma	Substitution - Missense
c.194G>A; p.G65E; 8:24309937-24309937	skin; face	malignant_melanoma	Substitution - Missense
c.1808G>A; p.G603E; 8:24341735-24341735	skin	malignant_melanoma	Substitution - Missense
c.1868C>A; p.A623D; 8:24343138-24343138	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.151G>A; p.E51K; 8:24309894-24309894	skin	malignant_melanoma	Substitution - Missense
c.478C>T; p.P160S; 8:24313482-24313482	skin	malignant_melanoma	Substitution - Missense
c.2196C>T; p.P732P; 8:24352004-24352004	skin	malignant_melanoma	Substitution - coding silent
c.1945G>A; p.E649K; 8:24343539-24343539	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1945G>A; p.E649K; 8:24343539-24343539	skin	malignant_melanoma	Substitution - Missense
c.598C>T; p.Q200*; 8:24320257-24320257	skin	malignant_melanoma	Substitution - Nonsense
c.1956C>T; p.I652I; 8:24343550-24343550	skin	malignant_melanoma	Substitution - coding silent
c.2006T>G; p.V669G; 8:24349879-24349879	skin	malignant_melanoma	Substitution - Missense
c.1956C>T; p.I652I; 8:24343550-24343550	skin	malignant_melanoma	Substitution - coding silent
c.1956C>T; p.I652I; 8:24343550-24343550	skin	malignant_melanoma	Substitution - coding silent
c.514G>A; p.D172N; 8:24313518-24313518	skin	malignant_melanoma	Substitution - Missense
c.166G>A; p.E56K; 8:24309909-24309909	skin	malignant_melanoma	Substitution - Missense
c.166G>A; p.E56K; 8:24309909-24309909	skin; mucosal	malignant_melanoma	Substitution - Missense
c.228G>A; p.K76K; 8:24310163-24310163	skin	malignant_melanoma	Substitution - coding silent
c.2160G>A; p.K720K; 8:24351292-24351292	skin	malignant_melanoma	Substitution - coding silent
c.103A>G; p.R35G; 8:24300030-24300030	skin	malignant_melanoma	Substitution - Missense
c.1880C>T; p.T627I; 8:24343150-24343150	skin	malignant_melanoma	Substitution - Missense
c.160G>A; p.E54K; 8:24309903-24309903	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1730G>A; p.G577E; 8:24341657-24341657	skin	malignant_melanoma	Substitution - Missense
c.1730G>A; p.G577E; 8:24341657-24341657	skin	malignant_melanoma	Substitution - Missense
c.1470C>T; p.F490F; 8:24335544-24335544	skin	malignant_melanoma	Substitution - coding silent
c.1411G>A; p.E471K; 8:24335485-24335485	skin	malignant_melanoma	Substitution - Missense
c.1521G>A; p.G507G; 8:24335595-24335595	skin	malignant_melanoma	Substitution - coding silent
c.973G>A; p.D325N; 8:24329985-24329985	skin	malignant_melanoma	Substitution - Missense
c.1540G>A; p.E514K; 8:24335614-24335614	skin	malignant_melanoma	Substitution - Missense
c.812_813TC>AT; p.F271Y; 8:24323925-24323926	skin; mucosal	malignant_melanoma	Substitution - Missense
c.444G>A; p.R148R; 8:24313448-24313448	skin	malignant_melanoma	Substitution - coding silent
c.252G>A; p.T84T; 8:24310187-24310187	skin	malignant_melanoma	Substitution - coding silent
c.2190G>A; p.M730I; 8:24351998-24351998	skin	malignant_melanoma	Substitution - Missense
c.947C>T; p.S316F; 8:24326610-24326610	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1485C>T; p.F495F; 8:24335559-24335559	skin	malignant_melanoma	Substitution - coding silent
c.562G>A; p.A188T; 8:24313566-24313566	skin	malignant_melanoma	Substitution - Missense
c.1825A>T; p.N609Y; 8:24341752-24341752	skin	malignant_melanoma	Substitution - Missense
c.822G>A; p.E274E; 8:24323935-24323935	skin	malignant_melanoma	Substitution - coding silent
c.822G>A; p.E274E; 8:24323935-24323935	skin	malignant_melanoma	Substitution - coding silent
c.1114C>T; p.P372S; 8:24331160-24331160	skin	malignant_melanoma	Substitution - Missense
c.235C>T; p.L79F; 8:24310170-24310170	skin	malignant_melanoma	Substitution - Missense
c.401G>A; p.G134E; 8:24313405-24313405	skin; neck	malignant_melanoma	Substitution - Missense
c.1986C>T; p.V662V; 8:24343580-24343580	skin	malignant_melanoma	Substitution - coding silent
c.1680G>A; p.M560I; 8:24341607-24341607	skin	malignant_melanoma	Substitution - Missense
c.193G>A; p.G65R; 8:24309936-24309936	skin	malignant_melanoma	Substitution - Missense
c.2141G>A; p.R714K; 8:24351273-24351273	skin	malignant_melanoma	Substitution - Missense
c.786G>A; p.K262K; 8:24323899-24323899	skin	malignant_melanoma	Substitution - coding silent
c.61G>A; p.E21K; 8:24299988-24299988	skin	malignant_melanoma	Substitution - Missense
c.2273C>T; p.T758I; 8:24353798-24353798	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1089G>A; p.M363I; 8:24330101-24330101	skin	malignant_melanoma	Substitution - Missense
c.513G>A; p.M171I; 8:24313517-24313517	skin	malignant_melanoma	Substitution - Missense
c.813C>T; p.F271F; 8:24323926-24323926	skin	malignant_melanoma	Substitution - coding silent
c.1998C>T; p.S666S; 8:24349871-24349871	skin	malignant_melanoma	Substitution - coding silent
c.1725G>A; p.W575*; 8:24341652-24341652	skin	malignant_melanoma	Substitution - Nonsense
c.276A>G; p.G92G; 8:24310211-24310211	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.403G>A; p.D135N; 8:24313407-24313407	skin	malignant_melanoma	Substitution - Missense
c.301A>T; p.I101F; 8:24310236-24310236	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.847G>T; p.V283F; 8:24323960-24323960	skin	malignant_melanoma	Substitution - Missense
c.907G>A; p.G303R; 8:24326570-24326570	skin	malignant_melanoma	Substitution - Missense
c.843G>A; p.G281G; 8:24323956-24323956	skin	malignant_melanoma	Substitution - coding silent
c.2092G>A; p.D698N; 8:24349965-24349965	skin	malignant_melanoma	Substitution - Missense
c.1686G>A; p.G562G; 8:24341613-24341613	skin	malignant_melanoma	Substitution - coding silent
c.2267C>T; p.P756L; 8:24353792-24353792	skin	malignant_melanoma	Substitution - Missense
c.2267C>T; p.P756L; 8:24353792-24353792	skin	malignant_melanoma	Substitution - Missense
c.1612G>A; p.G538R; 8:24339510-24339510	skin	malignant_melanoma	Substitution - Missense
c.1708T>C; p.S570P; 8:24341635-24341635	skin	malignant_melanoma	Substitution - Missense
c.1708T>C; p.S570P; 8:24341635-24341635	skin	malignant_melanoma	Substitution - Missense
c.1768C>T; p.P590S; 8:24341695-24341695	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1768C>T; p.P590S; 8:24341695-24341695	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1768C>T; p.P590S; 8:24341695-24341695	skin	malignant_melanoma	Substitution - Missense
c.603A>C; p.E201D; 8:24320262-24320262	skin	malignant_melanoma	Substitution - Missense
c.781G>A; p.D261N; 8:24323894-24323894	skin	malignant_melanoma	Substitution - Missense
c.479C>T; p.P160L; 8:24313483-24313483	skin	malignant_melanoma	Substitution - Missense
c.1641G>A; p.V547V; 8:24339539-24339539	skin	malignant_melanoma	Substitution - coding silent
c.1495C>T; p.H499Y; 8:24335569-24335569	skin	malignant_melanoma	Substitution - Missense
c.1218C>T; p.S406S; 8:24331264-24331264	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2028G>A; p.A676A; 8:24349901-24349901	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.501C>T; p.S167S; 8:24313505-24313505	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.895A>C; p.T299P; 8:24326558-24326558	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1213A>G; p.I405V; 8:24331259-24331259	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.217_218insA; p.N75fs*15; 8:24309960-24309961	stomach	carcinoma; intestinal_adenocarcinoma	Insertion - Frameshift
c.217_218insA; p.N75fs*15; 8:24309960-24309961	stomach	adenocarcinoma	Insertion - Frameshift
c.217_218insA; p.N75fs*15; 8:24309960-24309961	stomach	carcinoma; intestinal_adenocarcinoma	Insertion - Frameshift
c.217_218insA; p.N75fs*15; 8:24309960-24309961	stomach	carcinoma; intestinal_adenocarcinoma	Insertion - Frameshift
c.1039A>T; p.M347L; 8:24330051-24330051	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.479C>T; p.P160L; 8:24313483-24313483	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.676G>A; p.E226K; 8:24321245-24321245	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1822G>A; p.D608N; 8:24341749-24341749	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.1699C>T; p.Q567*; 8:24341626-24341626	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1962C>T; p.P654P; 8:24343556-24343556	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.681C>T; p.I227I; 8:24321250-24321250	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.2072C>G; p.S691C; 8:24349945-24349945	urinary_tract; bladder	carcinoma	Substitution - Missense

Oncogene database

COSMIC confirmed somatic mutation [Top]

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