Entrez Gene

Basic Information
Gene ID	10672
Name	GNA13
Synonymous	guanine nucleotide binding protein (G protein), alpha 13;GNA13;guanine nucleotide binding protein (G protein), alpha 13
Definition	G-protein subunit alpha-13\|g alpha-13\|guanine nucleotide-binding protein subunit alpha-13
Position	17q24.3
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC confirmed somatic mutation [Top]

c.1119G>T; p.Q373H; 17:65014272-65014272	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.992G>A; p.R331Q; 17:65014399-65014399	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.468C>T; p.S156S; 17:65053544-65053544	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.482C>G; p.A161G; 17:65053530-65053530	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.622G>T; p.E208*; 17:65014769-65014769	breast	carcinoma	Substitution - Nonsense
c.491G>A; p.R164Q; 17:65053521-65053521	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.1084G>A; p.V362M; 17:65014307-65014307	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.351A>G; p.Q117Q; 17:65053661-65053661	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.307C>T; p.R103*; 17:65053705-65053705	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.836G>A; p.R279Q; 17:65014555-65014555	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.79C>T; p.Q27*; 17:65056515-65056515	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1128A>G; p.L376L; 17:65014263-65014263	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1000C>T; p.R334C; 17:65014391-65014391	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.778C>T; p.R260*; 17:65014613-65014613	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.946C>A; p.P316T; 17:65014445-65014445	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1120C>A; p.L374I; 17:65014271-65014271	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.468C>T; p.S156S; 17:65053544-65053544	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.694C>T; p.R232C; 17:65014697-65014697	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.219G>T; p.G73G; 17:65056375-65056375	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.92C>T; p.S31F; 17:65056502-65056502	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.848A>T; p.N283I; 17:65014543-65014543	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; Burkitt_lymphoma	Substitution - Missense
c.665A>C; p.D222A; 17:65014726-65014726	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.665A>G; p.D222G; 17:65014726-65014726	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.665A>G; p.D222G; 17:65014726-65014726	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.211_228del18; p.I71_F76delIHGQDF; 17:65056366-65056383	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Deletion - In frame
c.1122delT; p.M375fs*>3; 17:65014269-65014269	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; follicular_lymphoma	Deletion - Frameshift
c.561+2T>C; p.?; 17:65018251-65018251	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Unknown
c.773A>G; p.E258G; 17:65014618-65014618	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; Burkitt_lymphoma	Substitution - Missense
c.473T>A; p.I158K; 17:65053539-65053539	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.886C>T; p.L296F; 17:65014505-65014505	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.267C>G; p.Y89*; 17:65056327-65056327	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.784A>G; p.T262A; 17:65014607-65014607	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.734T>C; p.F245S; 17:65014657-65014657	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.776A>T; p.D259V; 17:65014615-65014615	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; Burkitt_lymphoma	Substitution - Missense
c.142C>G; p.L48V; 17:65056452-65056452	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.526T>A; p.Y176N; 17:65018288-65018288	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; Burkitt_lymphoma	Substitution - Missense
c.124A>T; p.K42*; 17:65056470-65056470	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.689G>A; p.R230K; 17:65014702-65014702	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1034A>C; p.H345P; 17:65014357-65014357	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.1132T>C; p.*378R; 17:65014259-65014259	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Nonstop extension
c.265T>G; p.Y89D; 17:65056329-65056329	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1121T>A; p.L374H; 17:65014270-65014270	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.862C>A; p.L288M; 17:65014529-65014529	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.425T>C; p.F142S; 17:65053587-65053587	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; peripheral_T_cell_lymphoma_unspecified	Substitution - Missense
c.881A>T; p.D294V; 17:65014510-65014510	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.537T>G; p.D179E; 17:65018277-65018277	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.113_116TGTC>C; p.L38_S39>P; 17:65056478-65056481	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; Burkitt_lymphoma	Complex - deletion inframe
c.81G>C; p.Q27H; 17:65056513-65056513	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.547A>T; p.K183*; 17:65018267-65018267	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.923A>C; p.Y308S; 17:65014468-65014468	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.815T>C; p.F272S; 17:65014576-65014576	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.561+2T>A; p.?; 17:65018251-65018251	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Unknown
c.528T>A; p.Y176*; 17:65018286-65018286	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.875A>G; p.K292R; 17:65014516-65014516	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.113T>C; p.L38P; 17:65056481-65056481	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.252C>A; p.F84L; 17:65056342-65056342	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.542T>A; p.L181*; 17:65018272-65018272	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.101T>C; p.I34T; 17:65056493-65056493	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.101T>C; p.I34T; 17:65056493-65056493	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.914T>G; p.I305S; 17:65014477-65014477	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; Burkitt_lymphoma	Substitution - Missense
c.607A>G; p.T203A; 17:65014784-65014784	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.754T>G; p.F252V; 17:65014637-65014637	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; Burkitt_lymphoma	Substitution - Missense
c.590T>A; p.L197Q; 17:65014801-65014801	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.590T>A; p.L197Q; 17:65014801-65014801	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.881A>G; p.D294G; 17:65014510-65014510	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.551T>G; p.L184R; 17:65018263-65018263	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; Burkitt_lymphoma	Substitution - Missense
c.1134A>C; p.*378C; 17:65014257-65014257	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Nonstop extension
c.366G>C; p.M122I; 17:65053646-65053646	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.138G>C; p.K46N; 17:65056456-65056456	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1123A>C; p.M375L; 17:65014268-65014268	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.292G>T; p.V98L; 17:65053720-65053720	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.767T>A; p.L256H; 17:65014624-65014624	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.721A>G; p.T241A; 17:65014670-65014670	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.721A>G; p.T241A; 17:65014670-65014670	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.23G>T; p.R8L; 17:65056571-65056571	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.269G>T; p.S90I; 17:65056325-65056325	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.126G>T; p.K42N; 17:65056468-65056468	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.680G>A; p.R227K; 17:65014711-65014711	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.576_578delACA; p.Q194delQ; 17:65014813-65014815	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - In frame
c.783G>A; p.L261L; 17:65014608-65014608	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.783G>A; p.L261L; 17:65014608-65014608	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.936T>C; p.F312F; 17:65014455-65014455	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.634G>A; p.E212K; 17:65014757-65014757	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.580_582delCAA; p.Q194delQ; 17:65014809-65014811	large_intestine	carcinoma; adenocarcinoma	Deletion - In frame
c.494G>A; p.R165H; 17:65053518-65053518	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1096A>G; p.I366V; 17:65014295-65014295	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.363G>A; p.K121K; 17:65053649-65053649	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1001G>A; p.R334H; 17:65014390-65014390	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.393G>T; p.M131I; 17:65053619-65053619	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.712G>A; p.D238N; 17:65014679-65014679	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.712G>A; p.D238N; 17:65014679-65014679	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.394G>A; p.A132T; 17:65053618-65053618	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.778C>T; p.R260*; 17:65014613-65014613	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.778C>T; p.R260*; 17:65014613-65014613	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.628G>A; p.D210N; 17:65014763-65014763	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.931G>T; p.E311*; 17:65014460-65014460	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.931G>T; p.E311*; 17:65014460-65014460	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.491G>A; p.R164Q; 17:65053521-65053521	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.189C>T; p.T63T; 17:65056405-65056405	liver	carcinoma	Substitution - coding silent
c.189C>T; p.T63T; 17:65056405-65056405	liver	carcinoma	Substitution - coding silent
c.629A>G; p.D210G; 17:65014762-65014762	liver	carcinoma	Substitution - Missense
c.207G>A; p.R69R; 17:65056387-65056387	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.207G>A; p.R69R; 17:65056387-65056387	liver	carcinoma	Substitution - coding silent
c.1122T>G; p.L374L; 17:65014269-65014269	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.496C>T; p.R166*; 17:65053516-65053516	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.381C>T; p.T127T; 17:65053631-65053631	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.561A>T; p.P187P; 17:65018253-65018253	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.951C>T; p.H317H; 17:65014440-65014440	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.982G>C; p.E328Q; 17:65014409-65014409	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.779G>A; p.R260Q; 17:65014612-65014612	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1083C>T; p.D361D; 17:65014308-65014308	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.201G>C; p.Q67H; 17:65056393-65056393	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.286A>G; p.M96V; 17:65053726-65053726	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.927C>T; p.F309F; 17:65014464-65014464	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.982G>A; p.E328K; 17:65014409-65014409	skin	malignant_melanoma	Substitution - Missense
c.387C>T; p.A129A; 17:65053625-65053625	skin	malignant_melanoma	Substitution - coding silent
c.244G>A; p.E82K; 17:65056350-65056350	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.183G>C; p.K61N; 17:65056411-65056411	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.86G>A; p.R29H; 17:65056508-65056508	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.124A>G; p.K42E; 17:65056470-65056470	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1050C>G; p.I350M; 17:65014341-65014341	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.719T>C; p.V240A; 17:65014672-65014672	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1001G>A; p.R334H; 17:65014390-65014390	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.135G>A; p.V45V; 17:65056459-65056459	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.720G>A; p.V240V; 17:65014671-65014671	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.598A>G; p.R200G; 17:65014793-65014793	urinary_tract; bladder	carcinoma	Substitution - Missense
c.598A>G; p.R200G; 17:65014793-65014793	urinary_tract; bladder	carcinoma	Substitution - Missense
c.20C>T; p.S7L; 17:65056574-65056574	urinary_tract; bladder	carcinoma	Substitution - Missense
c.170G>T; p.G57V; 17:65056424-65056424	urinary_tract; bladder	carcinoma	Substitution - Missense
c.172G>A; p.E58K; 17:65056422-65056422	urinary_tract; bladder	carcinoma	Substitution - Missense
c.599G>A; p.R200K; 17:65014792-65014792	urinary_tract; bladder	carcinoma	Substitution - Missense
c.599G>A; p.R200K; 17:65014792-65014792	urinary_tract; bladder	carcinoma	Substitution - Missense
c.599G>A; p.R200K; 17:65014792-65014792	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.599G>A; p.R200K; 17:65014792-65014792	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.599G>A; p.R200K; 17:65014792-65014792	urinary_tract; bladder	carcinoma	Substitution - Missense

Oncogene database

COSMIC confirmed somatic mutation [Top]

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