| Gene information | Literature | Expression | lncRNA | Mutation | Homolog |
Basic Information | |
|---|---|
Gene ID | 10413 |
Name | YAP1 |
Synonymous | Yes-associated protein 1;YAP1;Yes-associated protein 1 |
Definition | 65 kDa Yes-associated protein|protein yorkie homolog|transcriptional coactivator YAP1|yes-associated protein 2|yes-associated protein YAP65 homolog|yorkie homolog |
Position | 11q13 |
Gene Type | protein-coding |
COSMIC confirmed somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.1019G>A; p.R340Q; 11:102227486-102227486 |
autonomic_ganglia | neuroblastoma | Substitution - Missense |
c.479T>A; p.L160H; 11:102114301-102114301 |
autonomic_ganglia | neuroblastoma | Substitution - Missense |
c.867G>T; p.R289R; 11:102206071-102206071 |
biliary_tract; gallbladder | carcinoma; adenocarcinoma | Substitution - coding silent |
c.964A>G; p.T322A; 11:102223715-102223715 |
biliary_tract; bile_duct | carcinoma; adenocarcinoma | Substitution - Missense |
c.1252C>T; p.P418S; 11:102229839-102229839 |
breast | carcinoma | Substitution - Missense |
c.723G>A; p.V241V; 11:102205927-102205927 |
breast | carcinoma | Substitution - coding silent |
c.723G>A; p.V241V; 11:102205927-102205927 |
breast | carcinoma | Substitution - coding silent |
c.675G>A; p.M225I; 11:102162558-102162558 |
central_nervous_system; medulla | primitive_neuroectodermal_tumour-medulloblastoma | Substitution - Missense |
c.377A>G; p.H126R; 11:102114199-102114199 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.1030A>G; p.T344A; 11:102227497-102227497 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.371G>A; p.R124Q; 11:102114193-102114193 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.313T>C; p.S105P; 11:102111161-102111161 |
haematopoietic_and_lymphoid_tissue; central_nervous_system | lymphoid_neoplasm; primary_central_nervous_system_lymphoma | Substitution - Missense |
c.1237G>T; p.G413*; 11:102229824-102229824 |
kidney | carcinoma; papillary_renal_cell_carcinoma | Substitution - Nonsense |
c.597G>A; p.W199*; 11:102162480-102162480 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Nonsense |
c.1026G>C; p.E342D; 11:102227493-102227493 |
kidney | carcinoma; papillary_renal_cell_carcinoma | Substitution - Missense |
c.1315A>G; p.T439A; 11:102229902-102229902 |
kidney | other; neoplasm | Substitution - Missense |
c.1171C>A; p.L391I; 11:102229758-102229758 |
kidney | other; neoplasm | Substitution - Missense |
c.706A>G; p.S236G; 11:102205910-102205910 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.680C>T; p.S227L; 11:102162563-102162563 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.971C>T; p.T324M; 11:102223722-102223722 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.1024G>A; p.E342K; 11:102227491-102227491 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.363G>A; p.Q121Q; 11:102114185-102114185 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - coding silent |
c.363G>T; p.Q121H; 11:102114185-102114185 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.413C>T; p.S138F; 11:102114235-102114235 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Missense |
c.1245G>A; p.E415E; 11:102229832-102229832 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - coding silent |
c.485A>G; p.Q162R; 11:102114307-102114307 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.964A>C; p.T322P; 11:102223715-102223715 |
oesophagus | carcinoma; adenocarcinoma | Substitution - Missense |
c.1248G>A; p.L416L; 11:102229835-102229835 |
oesophagus; lower_third | carcinoma; adenocarcinoma | Substitution - coding silent |
c.1348T>A; p.L450I; 11:102229935-102229935 |
ovary | carcinoma; serous_carcinoma | Substitution - Missense |
c.907C>T; p.Q303*; 11:102223658-102223658 |
pancreas | carcinoma | Substitution - Nonsense |
c.1246C>A; p.L416M; 11:102229833-102229833 |
pancreas | carcinoma | Substitution - Missense |
c.579C>T; p.I193I; 11:102162462-102162462 |
skin | malignant_melanoma | Substitution - coding silent |
c.783C>T; p.N261N; 11:102205987-102205987 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.1024G>A; p.E342K; 11:102227491-102227491 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.1070G>A; p.R357Q; 11:102227537-102227537 |
skin; acral | malignant_melanoma | Substitution - Missense |
c.460A>G; p.T154A; 11:102114282-102114282 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.1238G>C; p.G413A; 11:102229825-102229825 |
upper_aerodigestive_tract; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.1339C>T; p.L447F; 11:102229926-102229926 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.1069C>T; p.R357*; 11:102227536-102227536 |
urinary_tract; bladder | carcinoma | Substitution - Nonsense |
c.505G>A; p.D169N; 11:102114327-102114327 |
urinary_tract; bladder | carcinoma; transitional_cell_carcinoma | Substitution - Missense |
c.505G>A; p.D169N; 11:102114327-102114327 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.1248G>C; p.L416L; 11:102229835-102229835 |
urinary_tract; bladder | carcinoma | Substitution - coding silent |