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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

1021

Name

CDK6

Synonymous

cyclin-dependent kinase 6;CDK6;cyclin-dependent kinase 6

Definition

cell division protein kinase 6|serine/threonine-protein kinase PLSTIRE

Position

7q21-q22

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.417C>A; p.H139Q; 7:92725746-92725746

 breastcarcinomaSubstitution - Missense

c.352C>T; p.P118S; 7:92774713-92774713

 breastcarcinomaSubstitution - Missense

c.969G>A; p.L323L; 7:92615152-92615152

 breastcarcinomaSubstitution - coding silent

c.444A>T; p.P148P; 7:92725719-92725719

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.981+3C>T; p.?; 7:92615137-92615137

 central_nervous_system; brainglioma; astrocytoma_Grade_IVUnknown

c.492C>T; p.F164F; 7:92725671-92725671

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.793T>A; p.F265I; 7:92618113-92618113

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.652C>A; p.L218I; 7:92623082-92623082

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.469G>T; p.G157*; 7:92725694-92725694

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.807C>T; p.I269I; 7:92618099-92618099

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.672T>C; p.D224D; 7:92623062-92623062

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.658C>T; p.R220C; 7:92623076-92623076

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.540C>T; p.V180V; 7:92671533-92671533

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.138G>A; p.R46R; 7:92833186-92833186

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.250A>T; p.T84S; 7:92774815-92774815

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.431G>A; p.R144H; 7:92725732-92725732

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.431G>A; p.R144H; 7:92725732-92725732

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.749C>T; p.P250L; 7:92618157-92618157

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.658C>A; p.R220S; 7:92623076-92623076

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.588C>T; p.Y196Y; 7:92671485-92671485

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.260G>A; p.R87Q; 7:92774805-92774805

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.945G>A; p.P315P; 7:92615176-92615176

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.807C>T; p.I269I; 7:92618099-92618099

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.966G>T; p.E322D; 7:92615155-92615155

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.969G>A; p.L323L; 7:92615152-92615152

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.576C>G; p.L192L; 7:92671497-92671497

 lungcarcinoma; small_cell_carcinomaSubstitution - coding silent

c.337C>A; p.P113T; 7:92774728-92774728

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.608_609GG>CT; p.W203S; 7:92671464-92671465

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.620G>T; p.C207F; 7:92671453-92671453

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.53A>T; p.E18V; 7:92833271-92833271

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.588C>T; p.Y196Y; 7:92671485-92671485

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.641G>A; p.R214H; 7:92671432-92671432

 pancreascarcinoma; acinar_carcinomaSubstitution - Missense

c.511A>G; p.S171G; 7:92725652-92725652

 pancreascarcinomaSubstitution - Missense

c.883C>T; p.L295L; 7:92615238-92615238

 skinmalignant_melanomaSubstitution - coding silent

c.596C>T; p.P199L; 7:92671477-92671477

 skinmalignant_melanomaSubstitution - Missense

c.596C>T; p.P199L; 7:92671477-92671477

 skinmalignant_melanomaSubstitution - Missense

c.596C>T; p.P199L; 7:92671477-92671477

 skinmalignant_melanomaSubstitution - Missense

c.417C>T; p.H139H; 7:92725746-92725746

 skinmalignant_melanomaSubstitution - coding silent

c.748C>T; p.P250S; 7:92618158-92618158

 skinmalignant_melanomaSubstitution - Missense

c.929T>C; p.L310P; 7:92615192-92615192

 skinmalignant_melanomaSubstitution - Missense

c.22C>T; p.R8C; 7:92833302-92833302

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.741T>G; p.V247V; 7:92618165-92618165

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.460A>T; p.T154S; 7:92725703-92725703

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.914G>A; p.R305K; 7:92615207-92615207

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.270A>T; p.R90S; 7:92774795-92774795

 stomachcarcinoma; diffuse_adenocarcinomaSubstitution - Missense

c.473A>T; p.Q158L; 7:92725690-92725690

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.260G>A; p.R87Q; 7:92774805-92774805

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.183G>A; p.E61E; 7:92833141-92833141

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.700G>A; p.V234M; 7:92618206-92618206

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.826C>T; p.L276L; 7:92618080-92618080

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.52G>A; p.E18K; 7:92833272-92833272

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.195G>A; p.L65L; 7:92833129-92833129

 urinary_tract; bladdercarcinomaSubstitution - coding silent