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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

10155

Name

TRIM28

Synonymous

tripartite motif containing 28;TRIM28;tripartite motif containing 28

Definition

E3 SUMO-protein ligase TRIM28|KAP-1|KRAB [Kruppel-associated box domain]-associated protein 1|KRAB-associated protein 1|KRAB-interacting protein 1|KRIP-1|RING finger protein 96|TIF1-beta|nuclear corepressor KAP-1|protein phosphatase 1, regulatory subunit

Position

19q13.4

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.542A>G; p.H181R; 19:58545852-58545852

 adrenal_gland; adrenal_glandadrenal_cortical_carcinoma; functioningSubstitution - Missense

c.1475G>T; p.R492L; 19:58549053-58549053

 biliary_tract; bile_ductcarcinoma; adenocarcinomaSubstitution - Missense

c.1020G>A; p.K340K; 19:58548099-58548099

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.1310C>G; p.S437C; 19:58548579-58548579

 breastcarcinomaSubstitution - Missense

c.1771C>T; p.R591C; 19:58549439-58549439

 breastcarcinoma; HER-positive_carcinomaSubstitution - Missense

c.2229C>T; p.I743I; 19:58550182-58550182

 breastcarcinomaSubstitution - coding silent

c.1234C>T; p.R412C; 19:58548503-58548503

 breastcarcinomaSubstitution - Missense

c.2016C>T; p.L672L; 19:58549770-58549770

 breastcarcinomaSubstitution - coding silent

c.523G>A; p.E175K; 19:58545833-58545833

 breastcarcinomaSubstitution - Missense

c.1128C>G; p.L376L; 19:58548320-58548320

 breastcarcinomaSubstitution - coding silent

c.865A>C; p.K289Q; 19:58547817-58547817

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.673G>A; p.D225N; 19:58547462-58547462

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.382G>T; p.D128Y; 19:58545466-58545466

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.393G>T; p.E131D; 19:58545477-58545477

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.899T>A; p.L300Q; 19:58547851-58547851

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1147G>A; p.V383M; 19:58548339-58548339

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.393G>A; p.E131E; 19:58545477-58545477

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1122G>A; p.R374R; 19:58548314-58548314

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1926G>A; p.Q642Q; 19:58549594-58549594

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1569A>G; p.E523E; 19:58549147-58549147

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.889A>G; p.M297V; 19:58547841-58547841

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2120T>C; p.V707A; 19:58549962-58549962

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2090C>A; p.S697*; 19:58549844-58549844

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.1170G>A; p.K390K; 19:58548362-58548362

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.1170G>A; p.K390K; 19:58548362-58548362

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.521G>A; p.C174Y; 19:58545831-58545831

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.461C>G; p.T154S; 19:58545771-58545771

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1329G>A; p.M443I; 19:58548745-58548745

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1846G>A; p.G616S; 19:58549514-58549514

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.601C>T; p.R201W; 19:58547390-58547390

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1593C>T; p.T531T; 19:58549171-58549171

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.990G>A; p.R330R; 19:58548069-58548069

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.2148C>T; p.P716P; 19:58549990-58549990

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.359G>A; p.C120Y; 19:58545443-58545443

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1963G>C; p.A655P; 19:58549631-58549631

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1205C>T; p.A402V; 19:58548397-58548397

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.870T>G; p.R290R; 19:58547822-58547822

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.2142C>T; p.H714H; 19:58549984-58549984

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.2358C>T; p.I786I; 19:58550403-58550403

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.755A>T; p.Q252L; 19:58547629-58547629

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2237G>A; p.R746H; 19:58550190-58550190

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2294T>G; p.V765G; 19:58550247-58550247

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2154C>T; p.R718R; 19:58549996-58549996

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.2143G>A; p.E715K; 19:58549985-58549985

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1864G>A; p.D622N; 19:58549532-58549532

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.2116C>T; p.R706C; 19:58549958-58549958

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1873G>C; p.A625P; 19:58549541-58549541

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2111G>A; p.C704Y; 19:58549953-58549953

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1611G>A; p.A537A; 19:58549189-58549189

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1853C>T; p.P618L; 19:58549521-58549521

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1459C>T; p.R487*; 19:58549037-58549037

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1039C>T; p.R347C; 19:58548118-58548118

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1170G>A; p.K390K; 19:58548362-58548362

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.2067_2068insACTGGCG; p.V692fs*16; 19:58549821-58549822

 livercarcinomaInsertion - Frameshift

c.341-7C>T; p.?; 19:58545418-58545418

 livercarcinomaUnknown

c.1049C>G; p.S350C; 19:58548128-58548128

 livercarcinomaSubstitution - Missense

c.1768C>T; p.P590S; 19:58549436-58549436

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.859G>A; p.V287I; 19:58547811-58547811

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.544C>T; p.Q182*; 19:58545854-58545854

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1395G>A; p.V465V; 19:58548896-58548896

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1325C>T; p.P442L; 19:58548741-58548741

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.2434delC; p.P813fs*3; 19:58550479-58550479

 lungcarcinoma; adenocarcinomaDeletion - Frameshift

c.1216+2T>A; p.?; 19:58548410-58548410

 lungcarcinoma; adenocarcinomaUnknown

c.429C>T; p.A143A; 19:58545513-58545513

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1522G>C; p.V508L; 19:58549100-58549100

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1846G>A; p.G616S; 19:58549514-58549514

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1410-2A>G; p.?; 19:58548986-58548986

 lung; right_lower_lobecarcinoma; adenocarcinomaUnknown

c.2181C>T; p.S727S; 19:58550023-58550023

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.2196C>A; p.D732E; 19:58550149-58550149

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.426T>G; p.A142A; 19:58545510-58545510

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.2194-2A>T; p.?; 19:58550145-58550145

 oesophaguscarcinomaUnknown

c.252G>C; p.L84F; 19:58545009-58545009

 ovaryother; neoplasmSubstitution - Missense

c.2347C>T; p.Q783*; 19:58550392-58550392

 ovaryother; neoplasmSubstitution - Nonsense

c.1147G>A; p.V383M; 19:58548339-58548339

 pancreascarcinomaSubstitution - Missense

c.1128C>G; p.L376L; 19:58548320-58548320

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.791G>A; p.G264E; 19:58547665-58547665

 skinmalignant_melanomaSubstitution - Missense

c.2153G>A; p.R718H; 19:58549995-58549995

 skinmalignant_melanomaSubstitution - Missense

c.1200G>A; p.K400K; 19:58548392-58548392

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1474C>T; p.R492C; 19:58549052-58549052

 skinmalignant_melanomaSubstitution - Missense

c.1251A>C; p.S417S; 19:58548520-58548520

 skinmalignant_melanomaSubstitution - coding silent

c.1592C>T; p.T531I; 19:58549170-58549170

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1760C>T; p.A587V; 19:58549428-58549428

 skinmalignant_melanomaSubstitution - Missense

c.1842A>G; p.P614P; 19:58549510-58549510

 skinmalignant_melanomaSubstitution - coding silent

c.2202C>T; p.P734P; 19:58550155-58550155

 skinmalignant_melanomaSubstitution - coding silent

c.1128C>T; p.L376L; 19:58548320-58548320

 skinmalignant_melanomaSubstitution - coding silent

c.610G>A; p.E204K; 19:58547399-58547399

 skinmalignant_melanomaSubstitution - Missense

c.1310C>T; p.S437F; 19:58548579-58548579

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1498G>C; p.D500H; 19:58549076-58549076

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1570C>T; p.R524C; 19:58549148-58549148

 skinmalignant_melanomaSubstitution - Missense

c.670T>C; p.C224R; 19:58547459-58547459

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.525G>A; p.E175E; 19:58545835-58545835

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1030C>T; p.H344Y; 19:58548109-58548109

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.2085G>T; p.K695N; 19:58549839-58549839

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1663G>C; p.E555Q; 19:58549331-58549331

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1886G>A; p.R629H; 19:58549554-58549554

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.2326A>C; p.T776P; 19:58550279-58550279

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.1583C>A; p.A528D; 19:58549161-58549161

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.863A>G; p.Q288R; 19:58547815-58547815

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.2228T>C; p.I743T; 19:58550181-58550181

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1397C>G; p.S466*; 19:58548898-58548898

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.402C>A; p.F134L; 19:58545486-58545486

 thyroidcarcinomaSubstitution - Missense

c.2433G>C; p.E811D; 19:58550478-58550478

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2433G>C; p.E811D; 19:58550478-58550478

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2433G>C; p.E811D; 19:58550478-58550478

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2433G>C; p.E811D; 19:58550478-58550478

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.517C>T; p.L173L; 19:58545827-58545827

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1747G>A; p.E583K; 19:58549415-58549415

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1134G>A; p.M378I; 19:58548326-58548326

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1752T>G; p.G584G; 19:58549420-58549420

 urinary_tract; bladdercarcinomaSubstitution - coding silent