| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 9846 |
Name | GAB2 |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for GAB2 |
| Links to the AnimalTFDB for GAB2 |
Regulation From TransFac database | Gab-2(h) + ATP --> Gab-2(h){pY} + ADP (phosphorylation) | Grb-2(m) + Gab-2(h) <==> Grb-2(m):Gab-2(h) (binding) | Gab-2(h) --> Cdc42(h) (regulation of protein activity) | GAB2(h) --> Gab-2(h) (expression). | GAB2(h) --> Gab-2(h) (expression). |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 266 | Phosphotyrosine. | Swiss-Prot 53.0 | 405 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 643 | Phosphotyrosine | 15170389 | Phospho.ELM 6.0 | 623 | Phosphoserine (MAPK3) | 15356145 | Phospho.ELM 6.0 | 324 | Phosphotyrosine | 16497976 | Phospho.ELM 6.0 | 266 | Phosphotyrosine | 12522270 | Phospho.ELM 6.0 | 614 | Phosphotyrosine (ZAP70) | 11572860 | Phospho.ELM 6.0 | 293 | Phosphotyrosine | 11334882 | Phospho.ELM 6.0 | 476 | Phosphotyrosine | 11334882 | Phospho.ELM 6.0 | 584 | Phosphotyrosine | 11334882 | Phospho.ELM 6.0 | 452 | Phosphotyrosine | 11334882 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr11 |
Promoter: 77805914 - 77807914 | Agilent_014791 |
chr11 |
Promoter: 77805914 - 77807914 | GSE27584 |
chr11 |
Promoter: 77805914 - 77807914 | Agilent_014791_44K |