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dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

9314

Name

KLF4

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription factors   [Top]

The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget

Links to the hTFtarget for KLF4
Links to the AnimalTFDB for KLF4

Regulation From TransFac database

GKLF-isoform1(h) + p53(h) <==> p53(h):GKLF-isoform1(h) (binding)
GKLF-isoform1(h) --/ HBB(h) (DNA binding; transrepression).
GKLF-isoform1(h) --> CDKN1A(h) (DNA binding; transactivation).
GKLF-isoform1(h) --/ Hbb-b1(m) (DNA binding; transrepression).
KLF4(h) --> GKLF-isoform1(h) (expression).
KLF4(h) --> GKLF(h) (expression).
hsa-miR-7 --/ GKLF(h) (predicted)
HDAC1(h) + GKLFa(h) <==> HDAC1(h):GKLFa(h) (binding)
hdac2(h) + GKLFa(h) <==> hdac2(h):GKLFa(h) (binding)
GKLFa(h) --/ ITGAD(h) (DNA binding; transrepression).
KLF4(h) --> GKLFa(h) (expression).
HDAC1(h) + GKLF(h) <==> HDAC1(h):GKLF(h) (binding)
hdac2(h) + GKLF(h) <==> hdac2(h):GKLF(h) (binding)
GKLF(h) --> ITGAD(h) (DNA binding).
GKLF(h) --> SLC5A6(h) (DNA binding).
GKLF(h) + acetyl-CoA --> GKLF(h){aceK} + CoA (acetylation)
GKLF(h) --/ ENG(h) (transrepression)
GKLF(h) --/ ODC1(h) (transrepression)
GKLF(h) --> LAMA3(h) (transactivation)
GKLF(h) --> Odc1(m) (DNA binding; transactivation).
GKLF(h) --> GHRL(h) (DNA binding).
KLF4(h) --> GKLF(h) (expression).
KLF4(h) --> GKLF-isoform2(h) (expression).

Post Translational Modification   [Top]

There is no record for KLF4

Methylation Profile   [Top]

Chromosome

Location

Source

chr9

Promoter: 109291076 - 109293076Agilent_014791

chr9

Promoter: 109291076 - 109293076GSE27584


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