| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 9181 |
Name | ARHGEF2 |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for ARHGEF2 |
| Links to the AnimalTFDB for ARHGEF2 |
Regulation From TransFac database | RhoA(v.s.):GTP + LFP40(h) <==> RhoA(v.s.):GTP:LFP40(h) (binding) | RhoA(v.s.):GDP + LFP40(h) <==> RhoA(v.s.):GDP:LFP40(h) (binding) | Rac1(v.s.):GDP + LFP40(h) <==> Rac1(v.s.):GDP:LFP40(h) (binding) | Rac1(v.s.):GTP + LFP40(h) <==> Rac1(v.s.):GTP:LFP40(h) (binding) | LFP40(h) + p65PAK(m.s.) <==> LFP40(h):p65PAK(m.s.) (binding) | LFP40(h) + ATP --p65PAK(m.s.)--> LFP40(h){p} + ADP (phosphorylation) | LFP40(h) + PAK4(h) <==> LFP40(h):PAK4(h) (binding) | LFP40(h) + ATP --> LFP40(h){pS} + ADP (phosphorylation) | c-Myc(h) + LFP40(h) <==> c-Myc(h):LFP40(h) (binding) | ARHGEF2(h) --> LFP40(h) (expression). | RhoA(v.s.):GDP + GTP --LFP40(h)--> RhoA(v.s.):GTP + GDP (exchange) | Rac1(v.s.):GDP + GTP --LFP40(h)--> Rac1(v.s.):GTP + GDP (exchange) | rhoB(v.s.):GDP + GTP --LFP40(h)--> rhoB(v.s.):GTP + GDP (exchange) | RhoC(v.s.):GDP + GTP --LFP40(h)--> RhoC(v.s.):GTP + GDP (exchange) | PAK4(m.s.) + LFP40-xbb1(h) <==> PAK4(m.s.):LFP40-xbb1(h) (binding) | LFP40-xbb1(h) + ATP --PAK4-1(h)--> LFP40-xbb1(h){pS810} + ADP (phosphorylation) | ARHGEF2(h) --> LFP40-xbb1(h) (expression). | ARHGEF2(h) --> LFP40-isoform1(h) (expression). | ARHGEF2(h) --> LFP40-isoform2(h) (expression). | ARHGEF2(h) --> LFP40-isoform3(h) (expression). |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 163 | Phosphoserine. | Swiss-Prot 53.0 | 644 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 695 | Phosphoserine. | Swiss-Prot 53.0 | 885 | Phosphoserine (PAK1) | 14970201 | Phospho.ELM 6.0 | 163 | Phosphoserine | 16565220 | Phospho.ELM 6.0 | 695 | Phosphoserine | 16565220 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr1 |
Promoter: 154214075 - 154216075 | Agilent_014791 |
chr1 |
Promoter: 154214075 - 154216075 | GSE27584 |
chr1 |
Promoter: 154214075 - 154216075 | Agilent_014791_44K |
chr1 |
Promoter: 154214075 - 154216075 | E-GEOD-20553 |