Epithelial-Mesenchymal Transition gene database (dbEMT) Home
dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

9113

Name

LATS1

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription factors   [Top]

The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget

Links to the hTFtarget for LATS1
Links to the AnimalTFDB for LATS1

Regulation From TransFac database

Lats1(h) + ATP --cyclinB(h):Cdk1(h)--> Lats1(h){pS613} + ADP (phosphorylation)
cyclinB(h):Cdk1(h) + Lats1(h) <==> cyclinB(h):Cdk1(h):Lats1(h) (binding)
Lats1(h) + zyxin(h){p} <==> Lats1(h):zyxin(h){p} (binding)
sav1(h) + RASSF1-A(h) + MST2(h) + Lats1(h) <==> sav1(h):RASSF1-A(h):MST2(h):Lats1(h) (binding)
MOB1A(h) + Lats1(h) <==> MOB1A(h):Lats1(h) (binding)
LATS1(h) --> Lats1(h) (expression).
MOB1A(h) + Lats1(h) <==> MOB1A(h):Lats1(h) (binding)
MOB1A(h) + Lats1(h) <==> MOB1A(h):Lats1(h) (binding)
LATS1(h) --> Lats1(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

244Phosphoserine.Swiss-Prot 53.0
464Phosphoserine (By similarity).Swiss-Prot 53.0
909Phosphoserine (by STK3).Swiss-Prot 53.0
1079Phosphothreonine (by STK3).Swiss-Prot 53.0
244Phosphoserine15302935Phospho.ELM 6.0
464Phosphoserine15302935Phospho.ELM 6.0
1079Phosphothreonine15688006Phospho.ELM 6.0
613Phosphoserine15688006Phospho.ELM 6.0
909Phosphoserine15688006Phospho.ELM 6.0
633Phosphoserine15688006Phospho.ELM 6.0
1111Phosphoserine15688006Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr6

Promoter: 150080585 - 150082585Agilent_014791

chr6

Promoter: 150080585 - 150082585GSE27584

chr6

Promoter: 150080585 - 150082585Agilent_014791_44K

chr6

Promoter: 150080585 - 150082585PMID:15198948

chr6

Promoter: 150080585 - 150082585PMID:16192589

chr6

Promoter: 150080585 - 150082585PMID:15746036

chr6

Promoter: 150080585 - 150082585PMID:17049657


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