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dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

9112

Name

MTA1

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription factors   [Top]

The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget

Links to the hTFtarget for MTA1
Links to the AnimalTFDB for MTA1

Regulation From TransFac database

MTA-1long(h) + HIC-1-isoform2(h) <==> MTA-1long(h):HIC-1-isoform2(h) (binding)
MTA1(h) --> MTA-1long(h) (expression).
MAT1(h) + MTA-1(h) <==> MAT1(h):MTA-1(h) (binding)
MICoA(h) + MTA-1(h) <==> MICoA(h):MTA-1(h) (binding)
MTA-1(h) + MNAR(m.s.) <==> MTA-1(h):MNAR(m.s.) (binding)
HDAC1(h) + MTA-1(h) <==> HDAC1(h):MTA-1(h) (binding)
hdac2(h) + MTA-1(h) <==> hdac2(h):MTA-1(h) (binding)
HDAC1(m.s.) + MTA-1(h) <==> HDAC1(m.s.):MTA-1(h) (binding)
hdac2(m.s.) + MTA-1(h) <==> hdac2(m.s.):MTA-1(h) (binding)
ER-alpha(m.s.) + MTA-1(h) <==> ER-alpha(m.s.):MTA-1(h) (binding)
MTA-1(h) + ER-alpha(h) <==> MTA-1(h):ER-alpha(h) (binding)
Mi2-BETA(h) + MTA-1(h) <==> Mi2-BETA(h):MTA-1(h) (binding)
MTA-1(h) + p300(h) <==> MTA-1(h):p300(h) (binding)
MTA-1(h) --> BCAS3(h) (DNA binding; transactivation).
RbAp46(h) + RbAp48(h) + hdac2(h) + HDAC1(h) + MTA1L1(h) + MTA-1(h) + MBD3L(h) + MBD2a(h) <==> RbAp46(h):RbAp48(h):hdac2(h):HDAC1(h):MTA1L1(h):MTA-1(h):MBD3L(h):MBD2a(h) (binding)
MTA-1(h) --/ SNAI1(h) (transrepression)
NELF-C/D(h) + MTA-1(h) <==> NELF-C/D(h):MTA-1(h) (binding)
HIC-1-isoform2(h) + MTA-1(h) + mbd3(h) + Mi2-alpha(h) <==> HIC-1-isoform2(h):MTA-1(h):mbd3(h):Mi2-alpha(h) (binding)
MTA1(h) --> MTA-1(h) (expression).
NRG-Beta1(m.s.) --> MTA-1(h) (increase of abundance)
MTA1(h) --> MTA1S(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

386Phosphoserine.Swiss-Prot 53.0
467Phosphothreonine.Swiss-Prot 53.0
564Phosphothreonine.Swiss-Prot 53.0
576Phosphoserine.Swiss-Prot 53.0
576Phosphoserine15302935Phospho.ELM 6.0
467Phosphothreonine17081983Phospho.ELM 6.0
578Phosphothreonine17081983Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr14

Promoter: 104955731 - 104957731Agilent_014791

chr14

Promoter: 104955731 - 104957731GoldenGate_Methylation_Cancer_Panel_I

chr14

Promoter: 104955731 - 104957731GSE27584

chr14

Promoter: 104955731 - 104957731Agilent_014791_44K


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