Epithelial-Mesenchymal Transition gene database (dbEMT) Home
dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

8493

Name

PPM1D

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription factors   [Top]

The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget

Links to the hTFtarget for PPM1D
Links to the AnimalTFDB for PPM1D

Regulation From TransFac database

p38(h) + Wip1(h) <==> p38(h):Wip1(h) (binding)
Wip1(h) + Chk1(h) <==> Wip1(h):Chk1(h) (binding)
ATM(h) + Wip1(h) <==> ATM(h):Wip1(h) (binding)
Wip1(h) --/ TNF(h) (transrepression)
Wip1(h) --/ IL8(h) (transrepression)
Wip1(h) --/ IL6(h) (transrepression)
Wip1(h) --> RelA-p65(h){pS536} (decrease of phosphorylation)
PPM1D(h) --> Wip1(h) (expression).
RelA-p65(h) --> Wip1(h) (increase of abundance)
p38(m){p} --Wip1(h)--> p38(m) + p (dephosphorylation)
Chk1(h){pS345} --Wip1(h)--> p + Chk1(h) (dephosphorylation)
PPM1D(h) --> Wip1(h) (expression).
ATM(h){pS1981} --Wip1(h)--> ATM(h) + p (dephosphorylation)

Post Translational Modification   [Top]

There is no record for PPM1D

Methylation Profile   [Top]

Chromosome

Location

Source

chr17

Promoter: 56030836 - 56032836Agilent_014791

chr17

Promoter: 56030836 - 56032836GSE27584

chr17

Promoter: 56030836 - 56032836Agilent_014791_44K

chr17

Promoter: 56030836 - 56032836Agilent_014791


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