| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 8038 |
Name | ADAM12 |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for ADAM12 |
| Links to the AnimalTFDB for ADAM12 |
Regulation From TransFac database | ADAM12(h) --> ADAM12-isoform1(h) (expression). | Eve-1c(h) + ADAM12(h) <==> Eve-1c(h):ADAM12(h) (binding) | Eve-1d(h) + ADAM12(h) <==> Eve-1d(h):ADAM12(h) (binding) | ADAM12(h) --> ADAM12(h) (expression). | Abeta40(h) --/ ADAM12(h) (decrease of abundance) | IGFBP-3(h) + ADAM12-isoform2(h) <==> IGFBP-3(h):ADAM12-isoform2(h) (binding) | ADAM12(h) --> ADAM12-isoform2(h) (expression). | IGFBP-3(h) --ADAM12-isoform2(h)--> IGFBP3-p20(h) + protein remnants (cleavage) | IGFBP-3(h) --ADAM12-isoform2(h)--> IGFBP3-p10(h) + protein remnants (cleavage) |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 111 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 149 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 381 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 452 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 651 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 907 | Phosphotyrosine (by SRC) (By similarity). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr10 |
Promoter: 128066555 - 128068555 | Agilent_014791 |
chr10 |
Promoter: 128066555 - 128068555 | GSE27584 |
chr10 |
Promoter: 128066555 - 128068555 | GSE27584 |
chr10 |
Promoter: 128066555 - 128068555 | Agilent_014791_44K |