| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 7430 |
Name | EZR |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for EZR |
| Links to the AnimalTFDB for EZR |
Regulation From TransFac database | NHERF-1(h) + ezrin(h) <==> NHERF-1(h):ezrin(h) (binding) | ezrin(h) + MLCP(b) <==> ezrin(h):MLCP(b) (binding) | hamartin(m) + ezrin(h) <==> hamartin(m):ezrin(h) (binding) | p85(h) + p110alpha(h) + Hsp50(h) + Hsp90(h) + ezrin(h) + CD44(h) + ErbB2(h){p} <==> p85(h):p110alpha(h):Hsp50(h):Hsp90(h):ezrin(h):CD44(h):ErbB2(h){p} (binding) | p110alpha(h) + Hsp50(h) + ezrin(h) + CD44(h) + ErbB2(h){p} <==> p110alpha(h):Hsp50(h):ezrin(h):CD44(h):ErbB2(h){p} (binding) | Hsp50(h) + ezrin(h) + CD44(h) + ErbB2(h){p} <==> Hsp50(h):ezrin(h):CD44(h):ErbB2(h){p} (binding) | Gem(h) + ezrin(h) <==> Gem(h):ezrin(h) (binding) | Gem(h) + ezrin(h) <==> Gem(h):ezrin(h) (binding) | ezrin(h) + 2 ATP --> ezrin(h){pY146}{pY354} + 2 ADP (phosphorylation) | AMPKbeta-1(h) + ezrin(h) <==> AMPKbeta-1(h):ezrin(h) (binding) | GATE-16(h) + ezrin(h) <==> GATE-16(h):ezrin(h) (binding) | MCC1(h) + ezrin(h) <==> MCC1(h):ezrin(h) (binding) | ezrin(h) + ATP --> ezrin(h){pT567} + ADP (phosphorylation) | CD43(h) + ezrin(h) <==> CD43(h):ezrin(h) (binding) | ezrin(h) + ZAP-70(h) <==> ezrin(h):ZAP-70(h) (binding) | EZR(h) --> ezrin(h) (expression). | EZR(h) --> ezrin(h) (expression). | EZR(h) --> ezrin(h) (expression). | hsa-miR-183 --/ ezrin(h) (translational repression). |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 146 | Phosphotyrosine (by PDGFR). | Swiss-Prot 53.0 | 354 | Phosphotyrosine (by PDGFR). | Swiss-Prot 53.0 | 353 | Phosphotyrosine (EGFR) | 1382070 | Phospho.ELM 6.0 | 145 | Phosphotyrosine (Lck;EGFR) | 1382070;12560083 | Phospho.ELM 6.0 | 477 | Phosphotyrosine (Src) | 15623525 | Phospho.ELM 6.0 | 566 | Phosphothreonine (GRK-2;ROCK1;) | 10970850;15843435;15531580;14504278 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr6 |
Promoter: 159158747 - 159160747 | GSE27584 |
chr6 |
Promoter: 159158747 - 159160747 | Agilent_014791_44K |