| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 7158 |
Name | TP53BP1 |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for TP53BP1 |
| Links to the AnimalTFDB for TP53BP1 |
Regulation From TransFac database | p53(h) + 53BP1(h) <==> p53(h):53BP1(h) (binding) | 53BP1(h) + ATP --ATM(h)--> 53BP1(h){p} + ADP (phosphorylation) | h2ax(h){p} + 53BP1(h) <==> h2ax(h){p}:53BP1(h) (binding) | 53BP1(h) + STAT1(h) <==> 53BP1(h):STAT1(h) (binding) | BLM(h) + 53BP1(h) <==> BLM(h):53BP1(h) (binding) | 53BP1(h) + PTIP(h) <==> 53BP1(h):PTIP(h) (binding) | 53BP1(h) + BLM(h) + p53(h) <==> 53BP1(h):BLM(h):p53(h) (binding) | Nek1(h) + 53BP1(h) <==> Nek1(h):53BP1(h) (binding) | 53BP1(h) --> BRCA1(h) (DNA binding). | 53BP1(h) --> BRCA1(m) (DNA binding). | 53BP1(h) --> BRCA1(r) (DNA binding). | 53BP1(h) + p300(h) <==> 53BP1(h):p300(h) (binding) | 53BP1(h) + p53(m) <==> 53BP1(h):p53(m) (binding) | 53BP1(h) + sumo1(h) --> 53BP1(h){sumo} (sumoylation) | 53BP1(h) + ATP --> 53BP1(h){pS25} + ADP (phosphorylation) | TP53BP1(h) --> 53BP1(h) (expression). | 53BP1-isoform1(h) + PTIP-xbb2(h) <==> 53BP1-isoform1(h):PTIP-xbb2(h) (binding) | 53BP1-isoform1(h) + sumo1(h) --> 53BP1-isoform1(h){sumo} (sumoylation) | TP53BP1(h) --> 53BP1-isoform1(h) (expression). | TP53BP1(h) --> 53BP1-isoform2(h) (expression). |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 294 | Phosphoserine. | Swiss-Prot 53.0 | 316 | Phosphoserine. | Swiss-Prot 53.0 | 380 | Phosphoserine. | Swiss-Prot 53.0 | 500 | Phosphoserine. | Swiss-Prot 53.0 | 525 | Phosphoserine. | Swiss-Prot 53.0 | 552 | Phosphoserine. | Swiss-Prot 53.0 | 580 | Phosphoserine. | Swiss-Prot 53.0 | 635 | Phosphoserine. | Swiss-Prot 53.0 | 639 | Phosphoserine. | Swiss-Prot 53.0 | 640 | Phosphoserine. | Swiss-Prot 53.0 | 659 | Phosphoserine. | Swiss-Prot 53.0 | 660 | Phosphoserine. | Swiss-Prot 53.0 | 662 | Phosphoserine. | Swiss-Prot 53.0 | 750 | Phosphothreonine. | Swiss-Prot 53.0 | 751 | Phosphoserine. | Swiss-Prot 53.0 | 754 | Phosphoserine. | Swiss-Prot 53.0 | 755 | Phosphoserine. | Swiss-Prot 53.0 | 771 | Phosphoserine. | Swiss-Prot 53.0 | 782 | Phosphoserine. | Swiss-Prot 53.0 | 831 | Phosphoserine. | Swiss-Prot 53.0 | 993 | Phosphoserine. | Swiss-Prot 53.0 | 996 | Phosphothreonine. | Swiss-Prot 53.0 | 999 | Phosphoserine. | Swiss-Prot 53.0 | 1002 | Phosphoserine. | Swiss-Prot 53.0 | 1028 | Phosphoserine. | Swiss-Prot 53.0 | 1056 | Phosphothreonine. | Swiss-Prot 53.0 | 1094 | Phosphoserine. | Swiss-Prot 53.0 | 1114 | Phosphoserine. | Swiss-Prot 53.0 | 1362 | Phosphoserine. | Swiss-Prot 53.0 | 1426 | Phosphoserine. | Swiss-Prot 53.0 | 1430 | Phosphoserine. | Swiss-Prot 53.0 | 1634 | Phosphoserine. | Swiss-Prot 53.0 | 1635 | Phosphoserine. | Swiss-Prot 53.0 | 1638 | Phosphothreonine. | Swiss-Prot 53.0 | 1673 | Phosphoserine. | Swiss-Prot 53.0 | 1678 | Phosphoserine. | Swiss-Prot 53.0 | 1701 | Phosphoserine. | Swiss-Prot 53.0 | 1705 | Phosphoserine. | Swiss-Prot 53.0 | 1114 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 1028 | Phosphoserine | 15302935;17081983 | Phospho.ELM 6.0 | 294 | Phosphoserine | 15302935;17081983 | Phospho.ELM 6.0 | 552 | Phosphoserine | 15302935;17081983 | Phospho.ELM 6.0 | 525 | Phosphoserine | 15302935;17081983 | Phospho.ELM 6.0 | 6 | Phosphoserine (ATM) | 12697768 | Phospho.ELM 6.0 | 25 | Phosphoserine (ATM) | 12697768 | Phospho.ELM 6.0 | 29 | Phosphoserine (ATM) | 12697768 | Phospho.ELM 6.0 | 784 | Phosphoserine (ATM) | 12697768 | Phospho.ELM 6.0 | 500 | Phosphoserine | 15302935;17081983 | Phospho.ELM 6.0 | 1056 | Phosphothreonine | 15302935 | Phospho.ELM 6.0 | 831 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 380 | Phosphoserine | 15302935;17081983 | Phospho.ELM 6.0 | 316 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 782 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 1634 | Phosphoserine | 16094384 | Phospho.ELM 6.0 | 1635 | Phosphoserine | 16094384 | Phospho.ELM 6.0 | 1638 | Phosphothreonine | 16094384 | Phospho.ELM 6.0 | 222 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 265 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 379 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 523 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 548 | Phosphothreonine | 17081983 | Phospho.ELM 6.0 | 580 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 635 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 639 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 640 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 659 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 660 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 662 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 750 | Phosphothreonine | 17081983 | Phospho.ELM 6.0 | 751 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 754 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 755 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 899 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 1068 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 1094 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 1101 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 1214 | Phosphothreonine | 17081983 | Phospho.ELM 6.0 | 1216 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 1219 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 1362 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 1426 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 1430 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 1460 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 1462 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 1673 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 1678 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 1701 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 1705 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 1756 | Phosphothreonine | 17081983 | Phospho.ELM 6.0 | 1758 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 1759 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr15 |
Promoter: 41589528 - 41591528 | GSE27584 |
chr15 |
Promoter: 41589528 - 41591528 | Agilent_014791_44K |