| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 7042 |
Name | TGFB2 |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for TGFB2 |
| Links to the AnimalTFDB for TGFB2 |
Regulation From TransFac database | heparin + TGFbeta2(h) <==> heparin:TGFbeta2(h) (binding) | HSPGs(r) + TGFbeta2(h) <==> HSPGs(r):TGFbeta2(h) (binding) | TGFbeta2(h) + TGFbetaR-III(r) + TGFbetaR-II(h) <==> TGFbeta2(h):TGFbetaR-III(r):TGFbetaR-II(h) (binding) | TGFbeta2(h) + TGFbetaR-III(h) <==> TGFbeta2(h):TGFbetaR-III(h) (binding) | TGFbeta2(h) --> fibronectin(h) (increase of abundance) | TGFbeta2(h) --> PAI1(h) (increase of abundance) | TGFbeta2(h) --> Smad2(h){p} (increase of phosphorylation) | TGFbeta2(h) --> p15INK4b(r) (increase of abundance) | TGFbeta2(h) --/ Cdk2(r) (decrease of abundance) | TGFbeta2(h) --> pRb(r){p} (decrease of phosphorylation) | TGFbeta2(h) --> IL-11(h) (increase of secretion) | TGFbeta2(h) --> IL11(h) (transactivation) | TGFB2(h) --> TGFbeta2(h) (expression). | IL-1beta(h) --> TGFbeta2(h) (increase of secretion) | TNF-alpha(h) --> TGFbeta2(h) (increase of secretion) | IFNgamma(h) --> TGFbeta2(h) (decrease of secretion) | TGFB2(h) --> TGFbeta-2A(h) (expression). | TGFB2(h) --> TGFbeta-2B(h) (expression). | TGFB2(h) --> TGFB2(h) (expression). | hsa-miR-141 --/ TGFB2(h) (translational repression). |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 72 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 140 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 241 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr1 |
Promoter: 216584991 - 216586991 | Agilent_014791 |
chr1 |
Promoter: 216584991 - 216586991 | GoldenGate_Methylation_Cancer_Panel_I |
chr1 |
Promoter: 216584991 - 216586991 | GSE27584 |
chr1 |
Promoter: 216584991 - 216586991 | Agilent_014791_44K |