| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 6935 |
Name | ZEB1 |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for ZEB1 |
| Links to the AnimalTFDB for ZEB1 |
Regulation From TransFac database | ZEB (1124 AA)(h) --> IL2(h) (DNA binding). | ZEB (1124 AA)(h) --> Atp1a1(r) (DNA binding). | ZEB (1124 AA)(h) + NC2(h) <==> ZEB (1124 AA)(h):NC2(h) (binding). | ZEB (1124 AA)(h) --/ TP73(h) (DNA binding; transrepression). | ZEB (1124 AA)(h) --/ MIRN141(h) (DNA binding; transrepression). | ZEB (1124 AA)(h) --/ MIRN200C(h) (DNA binding; transrepression). | ZEB (1124 AA)(h) --> XDH(h) (DNA binding). | ZEB1(h) --> ZEB (1124 AA)(h) (expression). | ZEB1(h) --> ZEB (1154 AA)(h) (expression). | ZEB1(h) --/ MIRN141(h) (DNA binding; transrepression). | ZEB1(h) --> MIRN200C(h) (DNA binding; transactivation). | Ku80(h) + ZEB1(h) <==> Ku80(h):ZEB1(h) (binding) | ZEB1(h) --> XDH(h) (DNA binding). | ZEB1(h) --/ ZEB1(h) (transrepression) | ZEB1(h) --> ZEB1(h) (expression). | ZEB1(h) --> ZEB1(h) (expression). | hsa-miR-200a --/ ZEB1(h) (increase of mRNA decay). | hsa-miR-205 --/ ZEB1(h) (increase of mRNA decay). | hsa-miR-200b --/ ZEB1(h) (increase of mRNA decay). | hsa-miR-200c --/ ZEB1(h) (translational repression). |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 31 | Phosphoserine. | Swiss-Prot 53.0 | 33 | Phosphoserine. | Swiss-Prot 53.0 | 679 | Phosphoserine. | Swiss-Prot 53.0 | 347 | Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO). | Swiss-Prot 53.0 | 774 | Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO). | Swiss-Prot 53.0 | 679 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 31 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 33 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 698 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 704 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr10 |
Promoter: 31646648 - 31648648 | GSE27584 |
chr10 |
Promoter: 31646648 - 31648648 | Agilent_014791_44K |