Epithelial-Mesenchymal Transition gene database (dbEMT) Home
dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

6478

Name

SIAH2

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription factors   [Top]

The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget

Links to the hTFtarget for SIAH2
Links to the AnimalTFDB for SIAH2

Regulation From TransFac database

DCC(h) + Siah-2(h) <==> DCC(h):Siah-2(h) (binding)
Siah-2(h) + Ubc9(h) <==> Siah-2(h):Ubc9(h) (binding)
Siah-2(h) --/ DCC(h) (degradation)
Siah-2(h) + NACP(v.s.) <==> Siah-2(h):NACP(v.s.) (binding)
SIAH2(h) --> Siah-2(h) (expression).
wnt5a(m) --> Siah-2(h) (transactivation)
Synphilin-1(h) + n ubiquitin(v.s.) --Siah-2(h),ATP--> Synphilin-1(h){ub(n)} (ubiquitination)
Synphilin-1(h) + n ubiquitin(v.s.) --E1(v.s.),Ubc5B(h),Siah-2(h),ATP--> Synphilin-1(h){ub(n)} (ubiquitination)
NACP(v.s.) + ubiquitin(v.s.) --E1(v.s.),Ubc5B(h),Siah-2(h),ATP--> NACP(v.s.){ub(1)} (ubiquitination)

Post Translational Modification   [Top]

There is no record for SIAH2

Methylation Profile   [Top]

Chromosome

Location

Source

chr3

Promoter: 151963453 - 151965453Agilent_014791

chr3

Promoter: 151963453 - 151965453GSE27584

chr3

Promoter: 151963453 - 151965453Agilent_014791_44K


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