Epithelial-Mesenchymal Transition gene database (dbEMT) Home
dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

6347

Name

CCL2

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription factors   [Top]

The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget

Links to the hTFtarget for CCL2
Links to the AnimalTFDB for CCL2

Regulation From TransFac database

CCL2(h) --> MCP-1(h) (expression).
FcgammaRI alpha(h) --> MCP-1(h) (decrease of secretion)
FcgammaRIIA(h) --> MCP-1(h) (decrease of secretion)
FCgammaRIIIA(h) --> MCP-1(h) (decrease of secretion)
Murr1(h) --/ MCP-1(h) (decrease of abundance)
Nod2(m.s.) --> MCP-1(h) (increase of abundance)
GM-CSF(m.s.) --> MCP-1(h) (increase of abundance)
AKAP13(h) --> MCP-1(h) (increase of abundance)
IFNgamma(h) --> MCP-1(h) (increase of abundance)
IL-17A(h) --> MCP-1(h) (increase of secretion)
IL-17F(h) --> MCP-1(h) (increase of secretion)
TNF-alpha(m.s.) --> MCP-1(h) (increase of secretion)
IFNbeta(h) --> MCP-1(h) (increase of abundance)
LPS --> MCP-1(h) (decrease of secretion)
adiponectin(h) + MCP-1(h) <==> adiponectin(h):MCP-1(h) (binding)
heparin + MCP-1(h) <==> heparin:MCP-1(h) (binding)
CCL2(h) --> MCP-1(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

24Pyrrolidone carboxylic acid.Swiss-Prot 53.0
37N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

There is no record for CCL2



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