| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 6093 |
Name | ROCK1 |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for ROCK1 |
| Links to the AnimalTFDB for ROCK1 |
Regulation From TransFac database | RhoA(h):GTP + Rock-1(h) <==> RhoA(h):GTP:Rock-1(h) (binding) | Rock-1(h) --> GATA-4(m) (activation; phosphorylation) | Rock-1(h) --> GATA-5(m) (activation; phosphorylation) | Rock-1(h) + Aurora-A(h) <==> Rock-1(h):Aurora-A(h) (binding) | Rock-1(h) + Aurora-A(h) + DDX3(h) + HLR2(h) <==> Rock-1(h):Aurora-A(h):DDX3(h):HLR2(h) (binding) | Rock-1(h) --Caspase(h)--> protein remnants + Rock-1-p130(h) (cleavage) | Rock-1(h) --> protein remnants + Rock-1-p30(h) (cleavage) | Rock-1(h) --Caspase-3(m.s.)--> protein remnants + Rock-1-p30(h) (cleavage) | RhoA(m.s.):GTP + Rock-1(h) <==> RhoA(m.s.):GTP:Rock-1(h) (binding) | Rock-1(h) + Gem(h) <==> Rock-1(h):Gem(h) (binding) | caveolin-1(h) + Rock-1(h) <==> caveolin-1(h):Rock-1(h) (binding) | RhoE(m.s.) + Rock-1(h) <==> RhoE(m.s.):Rock-1(h) (binding) | ROCK1(h) --> Rock-1(h) (expression). | LIMK2(r) + ATP --Rock-1(h)--> LIMK2(r){pT505} + ADP (phosphorylation) | MLC(m.s.) + ATP --Rock-1(h)--> MLC(m.s.){pS} + ADP (phosphorylation) | Rock-1(h) --> Rock-1(h) (translocation) | Rock-1(h) + RhoE(m) <==> Rock-1(h):RhoE(m) (binding) | RhoE(m.s.) + Rock-1(h) <==> RhoE(m.s.):Rock-1(h) (binding) | ROCK1(h) --> Rock-1(h) (expression). | Rock-1(h) --> Rock-1(h) (translocation) | MLC(m.s.) + ATP --Rock-1(h)--> MLC(m.s.){pS} + ADP (phosphorylation) | RhoE(m) + 2 ATP --Rock-1(h)--> RhoE(m){pS7}{pS11} + 2 ADP (phosphorylation) |
Post Translational Modification [Top] | |||
There is no record for ROCK1 | |||
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr18 |
Promoter: 16945310 - 16947310 | Agilent_014791 |
chr18 |
Promoter: 16945310 - 16947310 | GSE27584 |
chr18 |
Promoter: 16945310 - 16947310 | Agilent_014791_44K |
chr18 |
Promoter: 16945310 - 16947310 | Agilent_014791 |