| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5921 |
Name | RASA1 |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for RASA1 |
| Links to the AnimalTFDB for RASA1 |
Regulation From TransFac database | p62Dok-1(m){pY} + RasGAP(h) <==> p62Dok-1(m){pY}:RasGAP(h) (binding) | RasGAP(h) + p62Dok-1(h){pY} <==> RasGAP(h):p62Dok-1(h){pY} (binding) | RasGAP(h) + p56Dok-2(h){pY} <==> RasGAP(h):p56Dok-2(h){pY} (binding) | Aurora-A(h) + RasGAP(h) <==> RasGAP(h):Aurora-A(h) (binding) | RasGAP(h) + Aurora-B(h) <==> RasGAP(h):Aurora-B(h) (binding) | survivin(h) + RasGAP(h) <==> survivin(h):RasGAP(h) (binding) | PDGFRbeta(v.s.) + RasGAP(h) <==> PDGFRbeta(v.s.):RasGAP(h) (binding) | huntingtin(h) + RasGAP(h) <==> huntingtin(h):RasGAP(h) (binding) | RasGAP(h) + Rab5(h) <==> RasGAP(h):Rab5(h) (binding) | RasGAP(h) + GTP:Rab5(h) <==> RasGAP(h):GTP:Rab5(h) (binding) | PLCgamma1(h){p} + RasGAP(h) <==> RasGAP(h):PLCgamma1(h){p} (binding) | RasGAP(h) + Rap1B(h) <==> RasGAP(h):Rap1B(h) (binding) | paxillin(m){pY118} + RasGAP(h) <==> paxillin(m){pY118}:RasGAP(h) (binding) | paxillin(m){pY31} + RasGAP(h) <==> paxillin(m){pY31}:RasGAP(h) (binding) | p190RhoGAP(r) + RasGAP(h) <==> p190RhoGAP(r):RasGAP(h) (binding) | MAGI-1(h) + RasGAP(h) <==> MAGI-1(h):RasGAP(h) (binding) | AIP5(h) + RasGAP(h) <==> AIP5(h):RasGAP(h) (binding) | RasGAP(h) + ABL-1b(h){pY} <==> RasGAP(h):ABL-1b(h){pY} (binding) | RasGAP(h) + bcr(h) <==> RasGAP(h):bcr(h) (binding) | RasGAP(h) + p62Dok-1(h) <==> RasGAP(h):p62Dok-1(h) (binding) | RasGAP(h) + ErbB1-p170(h){pY915}{pY998}{pY1016}{pY1125}{pY1172} <==> RasGAP(h):ErbB1-p170(h){pY915}{pY998}{pY1016}{pY1125}{pY1172} (binding) | ErbB2(h){pY1023}{pY1139}{pY1196}{pY1221}{pY1222} + RasGAP(h) <==> ErbB2(h){pY1023}{pY1139}{pY1196}{pY1221}{pY1222}:RasGAP(h) (binding) | RasGAP(h) + ErbB3-isoform1(h){pY868}{pY1197}{pY1222}{pY1260}{pY1276}{pY1289} <==> RasGAP(h):ErbB3-isoform1(h){pY868}{pY1197}{pY1222}{pY1260}{pY1276}{pY1289} (binding) | ErbB4(h){pY1284} + RasGAP(h) <==> ErbB4(h){pY1284}:RasGAP(h) (binding) | Pyk2(h) + RasGAP(h) <==> Pyk2(h):RasGAP(h) (binding) | RasGAP(h) + ATP --> RasGAP(h){pY} + ADP (phosphorylation) | RasGAP(h) + SOCS-1(h) <==> RasGAP(h):SOCS-1(h) (binding) | RasGAP(h) + SOCS-1(m) <==> RasGAP(h):SOCS-1(m) (binding) | RasGAP(h) + ATP --> RasGAP(h){pY460} + ADP (phosphorylation) | RASA1(h) --> RasGAP(h) (expression). | Efnb2(m.s.) --> RasGAP(h) (regulation of localization) | ephrin-B1(m.s.) --> RasGAP(h) (regulation of protein activity) | H-Ras(h):GTP --RasGAP(h)--> H-Ras(h):GDP + p (hydrolysis) | GTP:Rab5(h) --RasGAP(h)--> GDP:Rab5(h) + p (hydrolysis) | RASA1(h) --> RasGAP-L(h) (expression). | RASA1(h) --> RasGAP-S(h) (expression). | RASA1(h) --> RASA1(h) (expression). | hsa-miR-21 --/ RASA1(h) (translational repression). |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 615 | Phosphotyrosine. | Swiss-Prot 53.0 | 615 | Phosphotyrosine | 15592455 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr5 |
Promoter: 86598407 - 86600407 | Agilent_014791 |
chr5 |
Promoter: 86599022 - 86601022 | Agilent_014791 |
chr5 |
Promoter: 86598407 - 86600407 | GoldenGate_Methylation_Cancer_Panel_I |
chr5 |
Promoter: 86599022 - 86601022 | GoldenGate_Methylation_Cancer_Panel_I |
chr5 |
Promoter: 86599022 - 86601022 | GSE27584 |
chr5 |
Promoter: 86598407 - 86600407 | GSE27584 |