Epithelial-Mesenchymal Transition gene database (dbEMT) Home
dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

57447

Name

NDRG2

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription factors   [Top]

The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget

Links to the hTFtarget for NDRG2
Links to the AnimalTFDB for NDRG2

Regulation From TransFac database

NDRG2-isoform1(h) + 3 ATP --SGK-1(m.s.)--> NDRG2-isoform1(h){pT330}{pS332}{pT348} + 3 ADP (phosphorylation)
NDRG2-isoform1(h) + 2 ATP --RSK1(m.s.)--> NDRG2-isoform1(h){pS332}{pS350} + 2 ADP (phosphorylation)
NDRG2-isoform1(h) + 2 ATP --p70S6K1(m.s.)--> NDRG2-isoform1(h){pS332}{pS350} + 2 ADP (phosphorylation)
NDRG2-isoform1(h) + 2 ATP --AKT-1(m.s.)--> NDRG2-isoform1(h){pS332}{pT348} + 2 ADP (phosphorylation)
NDRG2(h) --> NDRG2-isoform1(h) (expression).
NDRG2(h) --> NDRG2(h) (expression).
NDRG2(h) --> NDRG2-isoform2(h) (expression).
NDRG2(h) --> NDRG2-isoform3(h) (expression).
NDRG2(h) --> NDRG2-isoform4(h) (expression).
NDRG2(h) --> NDRG2-isoform5(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

328Phosphoserine (By similarity).Swiss-Prot 53.0
330Phosphothreonine (By similarity).Swiss-Prot 53.0
332Phosphoserine (By similarity).Swiss-Prot 53.0
334Phosphothreonine (By similarity).Swiss-Prot 53.0
335Phosphoserine (By similarity).Swiss-Prot 53.0
338Phosphoserine (By similarity).Swiss-Prot 53.0
344Phosphoserine (By similarity).Swiss-Prot 53.0
348Phosphothreonine (By similarity).Swiss-Prot 53.0
350Phosphoserine (By similarity).Swiss-Prot 53.0
352Phosphoserine (By similarity).Swiss-Prot 53.0
353Phosphoserine (By similarity).Swiss-Prot 53.0
355Phosphoserine (By similarity).Swiss-Prot 53.0
357Phosphothreonine (By similarity).Swiss-Prot 53.0
350Phosphoserine15461589Phospho.ELM 6.0
346Phosphoserine15461589Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr14

Promoter: 20562604 - 20564604Agilent_014791

chr14

Promoter: 20562604 - 20564604GSE27584

chr14

Promoter: 20562604 - 20564604GSE27584

chr14

Promoter: 20563275 - 20565275GSE27584

chr14

Promoter: 20563275 - 20565275GSE27584

chr14

Promoter: 20563275 - 20565275GSE27584

chr14

Promoter: 20562604 - 20564604GSE27584

chr14

Promoter: 20562604 - 20564604GSE27584

chr14

Promoter: 20563275 - 20565275GSE27584


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