| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5629 |
Name | PROX1 |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for PROX1 |
| Links to the AnimalTFDB for PROX1 |
Regulation From TransFac database | prox1(h) --> SIX3(h) (transactivation) | LRH-1(h) + prox1(h) <==> LRH-1(h):prox1(h) (binding) | prox1(h) --/ CYP7A1(h) (transrepression) | HNF-4alpha(h) + prox1(h) <==> HNF-4alpha(h):prox1(h) (binding) | PPARdelta(h) + prox1(h) <==> PPARdelta(h):prox1(h) (binding) | RORalpha(h) + prox1(h) <==> RORalpha(h):prox1(h) (binding) | ERR1(h) + prox1(h) <==> ERR1(h):prox1(h) (binding) | ERR3(h) + prox1(h) <==> ERR3(h):prox1(h) (binding) | MR(h) + prox1(h) <==> MR(h):prox1(h) (binding) | PROX1(h) --> prox1(h) (expression). | prox1-xbb1(h) + pax6(z) <==> prox1-xbb1(h):pax6(z) (binding) | prox1-xbb1(h) --> CRY-betB1(c) (DNA binding; transactivation). | prox1-xbb1(h) --> FGFR3(m) (DNA binding; transactivation). | PROX1(h) --> prox1-xbb1(h) (expression). | PROX1(h) --> prox1-isoform1(h) (expression). |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 177 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 179 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 291 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 511 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 514 | Phosphoserine (By similarity). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr1 |
Promoter: 212226983 - 212228983 | Agilent_014791 |
chr1 |
Promoter: 212226983 - 212228983 | GSE27584 |