Epithelial-Mesenchymal Transition gene database (dbEMT) Home
dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

5290

Name

PIK3CA

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription factors   [Top]

The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget

Links to the hTFtarget for PIK3CA
Links to the AnimalTFDB for PIK3CA

Regulation From TransFac database

p110alpha(h) + H-Ras(h):GTP <==> p110alpha(h):H-Ras(h):GTP (binding)
p110alpha(h) + H-Ras(m.s.) <==> p110alpha(h):H-Ras(m.s.) (binding)
p110alpha(h) --> p85alpha(h) (binding)
p110alpha(h) + ER-alpha(h) <==> p110alpha(h):ER-alpha(h) (binding)
p85(h) + p110alpha(h) + Hsp50(h) + Hsp90(h) + ezrin(h) + CD44(h) + ErbB2(h){p} <==> p85(h):p110alpha(h):Hsp50(h):Hsp90(h):ezrin(h):CD44(h):ErbB2(h){p} (binding)
p110alpha(h) + Hsp50(h) + ezrin(h) + CD44(h) + ErbB2(h){p} <==> p110alpha(h):Hsp50(h):ezrin(h):CD44(h):ErbB2(h){p} (binding)
p110alpha(h) + ATP --> p110alpha(h){pY} + ADP (phosphorylation)
Pik3ca(h) --> p110alpha(h) (expression).
G-alpha-q(m) --> p110alpha(h) (binding)
VEGF-A(m.s.) --> p110alpha(h) (increase of abundance)
Pik3ca(h) --> p110alpha(h) (expression).

Post Translational Modification   [Top]

There is no record for PIK3CA

Methylation Profile   [Top]

Chromosome

Location

Source

chr3

Promoter: 180347505 - 180349505Agilent_014791

chr3

Promoter: 180347505 - 180349505GSE27584

chr3

Promoter: 180347505 - 180349505Agilent_014791


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