Epithelial-Mesenchymal Transition gene database (dbEMT) Home
dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

50616

Name

IL22

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription factors   [Top]

The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget

Links to the hTFtarget for IL22
Links to the AnimalTFDB for IL22

Regulation From TransFac database

IL-22(h) --> STAT3(h) (activation; phosphorylation)
IL-22(h) --> STAT1(h) (activation; phosphorylation)
IL-22(h) + IL-10R2(h) <==> IL-22(h):IL-10R2(h) (binding)
IL-22(h) --> STAT5(h) (activation; phosphorylation)
IL-22(h) + IL-22BP(h) <==> IL-22(h):IL-22BP(h) (binding)
IL-22(h) + IL-22R1(h) <==> IL-22(h):IL-22R1(h) (binding)
IL-22(h) + IL-22R1(h) + IL-10R2(h) <==> IL-22(h):IL-22R1(h):IL-10R2(h) (binding)
IL-22(h) --> Jak1(r){pY} (activation; phosphorylation)
IL-22(h) --> Tyk2(r){pY} (activation; phosphorylation)
IL22(h) --> IL-22(h) (expression).
IL-22(h) --> NOS2(h) (transactivation)
IL-22(h) + IL-10R2(h) <==> IL-22(h):IL-10R2(h) (binding)
IL-22R1(h) + IL-22(h) <==> IL-22R1(h):IL-22(h) (binding)
IL-10R2(m.s.) + IL-22R1(h) + IL-22(h) <==> IL-10R2(m.s.):IL-22R1(h):IL-22(h) (binding)
IL-22(h) --> STAT1(h){pY701} (increase of phosphorylation)
IL-22(h) --> STAT3(h){pY705} (increase of phosphorylation)
IL-22(h) --> STAT5(h){pY} (increase of phosphorylation)
IL-22(h) --> ERK1(h){pT202}{pY204} (increase of phosphorylation)
IL-22(h) --> ERK2(h){pT185}{pY187} (increase of phosphorylation)
IL-22(h) --> AKT(h){p} (increase of phosphorylation)
IL-22(h) --> IL6(h) (transactivation)
IL-22(h) --> IL8(h) (transactivation)
IL-22(h) --> TNF(h) (transactivation)
IL-22(h) --> SOCS3(h) (transactivation)
IL-22(h) --> IL-8(h) (increase of abundance)
IL-22(h) --> STAT1(m){pY} (increase of phosphorylation)
IL-22(h) --> STAT3(m){pY705} (increase of phosphorylation)
IL-22(h) --> STAT5(m){pY} (increase of phosphorylation)
2 IL-22(h) <==> (IL-22(h))2 (binding)
4 IL-22(h) <==> (IL-22(h))4 (binding)
IL-22(h) + IL-22BP-isoform2(h) <==> IL-22(h):IL-22BP-isoform2(h) (binding)
IL22(h) --> IL-22(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

54N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
68N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
97N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

There is no record for IL22



')