| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 4904 |
Name | YBX1 |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for YBX1 |
| Links to the AnimalTFDB for YBX1 |
Regulation From TransFac database | YB-1B(h) --/ Vegfa(m) (DNA binding; transrepression). | YB-1B(h) + calmodulin(b) <==> YB-1B(h):calmodulin(b) (binding) | AUF1-p37(m.s.) + YB-1B(h) <==> AUF1-p37(m.s.):YB-1B(h) (binding) | AUF1-p40(m.s.) + YB-1B(h) <==> AUF1-p40(m.s.):YB-1B(h) (binding) | YBX1(h) --> YB-1B(h) (expression). | YB-1(h) --> Mmp2(r) (DNA binding; transregulation). | AP-2alphaA(h) + YB-1(h) <==> AP-2alphaA(h):YB-1(h) (binding). | YB-1(h) + YB-1(h) <==> YB-1(h):YB-1(h) (binding). | PCNA(h) + YB-1(h) <==> PCNA(h):YB-1(h) (binding) | PCNA(h) + YB-1(h) <==> PCNA(h):YB-1(h) (binding) | YB-1(h) --> SLC6A4(h) (DNA binding; transactivation). | YB-1(h) --> ABCB1(h) (DNA binding). | YBX1(h) --> YB-1(h) (expression). | PCNA(h) + YB-1(h) <==> PCNA(h):YB-1(h) (binding) | PCNA(h) + YB-1(h) <==> PCNA(h):YB-1(h) (binding) | YB-1(h) --> ABCB1(h) (DNA binding). | brca1(m.s.) + YB-1(h) <==> brca1(m.s.):YB-1(h) (binding) | YB-1(h) --> FAS(h) (DNA binding). | AUF1-p37(m.s.) + YB-1(h) <==> AUF1-p37(m.s.):YB-1(h) (binding) | YB-1(h) + ATP --> YB-1(h){pS102} + ADP (phosphorylation) | YB-1(h) --> ErbB2(h) (increase of abundance) | YB-1(h) --> ErbB1(h) (increase of abundance) | YB-1(h) --> ERK1(h){pT202}{pY204} (increase of phosphorylation) | YB-1(h) --> ERK2(h){pT185}{pY187} (increase of abundance) | YB-1(h) --> h2ax(h){pS140} (decrease of phosphorylation) | YB-1(h) --> STAT3(h){pS727} (increase of phosphorylation) | YB-1(h) --> Mcl-1(h) (increase of abundance) | YB-1(h) --> mTOR(h) (increase of abundance) | YB-1(h) --> mTOR(h){pS2448} (increase of phosphorylation) | YB-1(h) --> GUCY1B3(h) (DNA binding). | YB-1(h) --> EGFR(h) (DNA binding). | YB-1(h) --> CCNA2(h) (DNA binding). | YB-1(h) --> CCNB1(h) (DNA binding; transactivation). | YB-1(h) --> CCL5(h) (DNA binding). | YB-1(h) --> MET(h) (DNA binding). | YB-1(h) --> SMAD7(r) (DNA binding). | YB-1(h) --> PTPN1(h) (DNA binding). | YB-1(h) --/ ABCC2(r) (DNA binding; transrepression). | YB-1(h) --> Pik3ca(h) (DNA binding). | YB-1(h) --> MMP13(h) (DNA binding). | YB-1(h) --> H2-M3(m) (DNA binding). | YB-1(h) --> ACTA2(h) (DNA binding). | YBX1(h) --> YB-1(h) (expression). |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 102 | Phosphoserine (by PKB/AKT1). | Swiss-Prot 53.0 | 162 | Phosphotyrosine. | Swiss-Prot 53.0 | 165 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 174 | Phosphoserine. | Swiss-Prot 53.0 | 176 | Phosphoserine. | Swiss-Prot 53.0 | 314 | Phosphoserine. | Swiss-Prot 53.0 | 161 | Phosphotyrosine | 15592455 | Phospho.ELM 6.0 | 101 | Phosphoserine | 15806160;17081983 | Phospho.ELM 6.0 | 164 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 173 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 175 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 312 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 313 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr1 |
Promoter: 42919153 - 42921153 | Agilent_014791 |
chr1 |
Promoter: 42919153 - 42921153 | GSE27584 |
chr1 |
Promoter: 42919153 - 42921153 | Agilent_014791_44K |