| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 4853 |
Name | NOTCH2 |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for NOTCH2 |
| Links to the AnimalTFDB for NOTCH2 |
Regulation From TransFac database | Notch2(h) --> Notch2TM(h) + Notch2EC(h) (cleavage) | Notch2(h) --PACE(h)--> Notch2EC(h) + Notch2TM(h) (cleavage) | NOTCH2(h) --> Notch2(h) (expression). | MEF2C(m) + Notch2(h) <==> MEF2C(m):Notch2(h) (binding) | NOTCH2(h) --> Notch2(h) (expression). | NOTCH2(h) --> NOTCH2(h) (expression). | hsa-miR-34a --/ NOTCH2(h) (translational repression). |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 46 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 155 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 733 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 1102 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 1465 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 1808 | Phosphothreonine. | Swiss-Prot 53.0 | 1841 | Phosphoserine. | Swiss-Prot 53.0 | 1842 | Phosphoserine. | Swiss-Prot 53.0 | 1845 | Phosphoserine. | Swiss-Prot 53.0 | 2070 | Phosphoserine. | Swiss-Prot 53.0 | 2078 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 1808 | Phosphothreonine | 15302935 | Phospho.ELM 6.0 | 2070 | Phosphoserine | 15302935 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr1 |
Promoter: 120413299 - 120415299 | GoldenGate_Methylation_Cancer_Panel_I |
chr1 |
Promoter: 120413299 - 120415299 | Agilent_014791_44K |
chr1 |
Promoter: 120413299 - 120415299 | E-GEOD-20553 |