Epithelial-Mesenchymal Transition gene database (dbEMT) Home
dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

4613

Name

MYCN

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription factors   [Top]

The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget

Links to the hTFtarget for MYCN
Links to the AnimalTFDB for MYCN

Regulation From TransFac database

N-Myc(h) + Max-isoform2(h) <==> N-Myc(h):Max-isoform2(h) (binding).
N-Myc(h) + Max(m) <==> N-Myc(h):Max(m) (binding).
N-Myc(h) + Max-isoform1(h) <==> N-Myc(h):Max-isoform1(h) (binding).
N-Myc(h) + Nmi(h) <==> N-Myc(h):Nmi(h) (binding).
N-Myc(h) --> MUC5B(h) (DNA binding).
MYCN(h) --> N-Myc(h) (expression).
MYCN(h) --> MYCN(h) (expression).
hsa-miR-101 --/ MYCN(h) (predicted)
hsa-miR-202 --/ MYCN(h) (predicted)
hsa-miR-34a --/ MYCN(h) (translational repression).
N-Myc(h) --> MDM2(h) (DNA binding; transactivation).
N-Myc(h) --> PTK2(h) (DNA binding; transregulation).
MYCN(h) --> N-Myc(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

58Phosphothreonine.Swiss-Prot 53.0
62Phosphoserine.Swiss-Prot 53.0
261Phosphoserine (by CK2).Swiss-Prot 53.0
263Phosphoserine (by CK2).Swiss-Prot 53.0
58Phosphothreonine15302935Phospho.ELM 6.0
62Phosphoserine15302935Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr2

Promoter: 15996634 - 15998634Agilent_014791

chr2

Promoter: 15996634 - 15998634GoldenGate_Methylation_Cancer_Panel_I

chr2

Promoter: 15996634 - 15998634GSE27584


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