Epithelial-Mesenchymal Transition gene database (dbEMT) Home
dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

4605

Name

MYBL2

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription factors   [Top]

The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget

Links to the hTFtarget for MYBL2
Links to the AnimalTFDB for MYBL2

Regulation From TransFac database

B-Myb(h) + NCOR1(h) <==> B-Myb(h):NCOR1(h) (binding)
B-Myb(h) --> c-myb(h) (DNA binding).
B-Myb(h) --> IGFBP5(h) (DNA binding).
MYBL2(h) --> B-Myb(h) (expression).
C/EBPalpha(h) --/ B-Myb(h) (decrease of abundance)
B-Myb(h) --/ COL1A2(h) (transrepression;)
MYBL2(h) --> B-Myb(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

266Phosphothreonine.Swiss-Prot 53.0
393Phosphoserine.Swiss-Prot 53.0
440Phosphothreonine (by CDK2).Swiss-Prot 53.0
444Phosphothreonine (by CDK2).Swiss-Prot 53.0
487Phosphothreonine (by CDK2).Swiss-Prot 53.0
494Phosphothreonine (by CDK2).Swiss-Prot 53.0
520Phosphothreonine (by CDK2).Swiss-Prot 53.0
577Phosphoserine (by CDK2).Swiss-Prot 53.0
266Phosphothreonine17081983Phospho.ELM 6.0
444Phosphothreonine (CDK2)9840932Phospho.ELM 6.0
487Phosphothreonine (CDK2)9840932Phospho.ELM 6.0
494Phosphothreonine (CDK2)9840932Phospho.ELM 6.0
577Phosphoserine (CDK2)9840932Phospho.ELM 6.0
393Phosphoserine15302935Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr20

Promoter: 41727623 - 41729623Agilent_014791

chr20

Promoter: 41727623 - 41729623GoldenGate_Methylation_Cancer_Panel_I

chr20

Promoter: 41727623 - 41729623GSE27584

chr20

Promoter: 41727623 - 41729623Agilent_014791_44K


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