| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 4040 |
Name | LRP6 |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for LRP6 |
| Links to the AnimalTFDB for LRP6 |
Regulation From TransFac database | Dkk-1(h) + LRP6(h) <==> Dkk-1(h):LRP6(h) (binding) | LRP6(h) + Wnt-1(m) <==> LRP6(h):Wnt-1(m) (binding) | Dkk-1(x) + LRP6(h) <==> Dkk-1(x):LRP6(h) (binding) | Dkk-2(m) + LRP6(h) <==> Dkk-2(m):LRP6(h) (binding) | Fz8(m) + Wnt-1(m) + LRP6(h) <==> Fz8(m):Wnt-1(m):LRP6(h) (binding) | axin(m) + LRP6(h) <==> axin(m):LRP6(h) (binding) | 2 LRP6(h) <==> LRP6(h):LRP6(h) (binding) | LRP6(h) + Wnt-7A(h) + Fz5(h) <==> LRP6(h):Wnt-7A(h):Fz5(h) (binding) | LRP6(h) + Wnt-8A(x) + Fz5(h) <==> LRP6(h):Wnt-8A(x):Fz5(h) (binding) | LRP6(h) + Wnt-5A(x) + Fz5(h) <==> LRP6(h):Wnt-5A(x):Fz5(h) (binding) | LRP6(h) + Wnt-11(x) + Fz5(h) <==> LRP6(h):Wnt-11(x):Fz5(h) (binding) | LRP6(h) + Wnt-8A(x) + Fz4(h) <==> LRP6(h):Wnt-8A(x):Fz4(h) (binding) | LRP6(h) + ATP --> LRP6(h){pS1490} + ADP (phosphorylation) | Wnt-3A(m) + LRP6(h) <==> LRP6(h):Wnt-3A(m) (binding) | LRP6(h) --> LRP6(h) (expression). | LRP6(h) + ATP --> LRP6(h){pS1490} + ADP (phosphorylation) | LRP6(h) + FZ1(h) <==> LRP6(h):FZ1(h) (binding) | LRP6(h) --> LRP6(h) (expression). |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 42 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 81 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 281 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 433 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 486 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 692 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 859 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 865 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 926 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 1039 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr12 |
Promoter: 12310513 - 12312513 | Agilent_014791 |
chr12 |
Promoter: 12310513 - 12312513 | GSE27584 |
chr12 |
Promoter: 12310513 - 12312513 | Agilent_014791_44K |
chr12 |
Promoter: 12310513 - 12312513 | Agilent_014791 |