| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3791 |
Name | KDR |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for KDR |
| Links to the AnimalTFDB for KDR |
Regulation From TransFac database | VEGFR-2(h) + VRAP(h) <==> VEGFR-2(h):VRAP(h) (binding) | VEGFR-2(h) + Sck(h) <==> VEGFR-2(h):Sck(h) (binding) | VEGF-165(h) + VEGFR-2(h) <==> VEGF-165(h):VEGFR-2(h) (binding) | VEGFR-2(h) + Grb-2(pg) <==> VEGFR-2(h):Grb-2(pg) (binding) | VEGFR-2(h) + Nck-1(pg) <==> VEGFR-2(h):Nck-1(pg) (binding) | VEGFR-2(h) + GAP(pg) <==> VEGFR-2(h):GAP(pg) (binding) | VEGFR-2(h) + SHP-1(pg) <==> VEGFR-2(h):SHP-1(pg) (binding) | VEGFR-2(h) + SHP-2(pg) <==> VEGFR-2(h):SHP-2(pg) (binding) | VEGFR-2(h) + beta3-integrin(h) <==> VEGFR-2(h):beta3-integrin(h) (binding) | IQGAP1(h) + VEGFR-2(h) <==> IQGAP1(h):VEGFR-2(h) (binding) | VEGFR-2(h) + ATP --> VEGFR-2(h){pY1054} + ADP (phosphorylation) | VEGFR-2(h) + ATP --> VEGFR-2(h){pY} + ADP (phosphorylation) | VEGFR-2(h) + ATP --> VEGFR-2(h){pY951}{pY1175} + ADP (phosphorylation) | KDR(h) --> VEGFR-2(h) (expression). | myoferlin(h) --> VEGFR-2(h) (increase of abundance) | c-Cbl(m) --> VEGFR-2(h) (increase of abundance) | dynamin2(h) --/ VEGFR-2(h) (decrease of abundance) | p52Shc(pg) + NTP --VEGFR-2(h)--> p52Shc(pg){p} + NDP (phosphorylation) | p42Shc(pg) + NTP --VEGFR-2(h)--> p42Shc(pg){p} + NDP (phosphorylation) | VEGFR-2(h) + ATP --> VEGFR-2(h){pY} + ADP (automodification) | KDR(h) --> VEGFR-2(h) (expression). | myoferlin(h) --> VEGFR-2(h) (increase of abundance) |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 46 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 66 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 96 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 143 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 158 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 245 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 318 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 374 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 395 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 511 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 523 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 580 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 613 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 619 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 631 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 675 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 704 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 721 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 1059 | Phosphotyrosine (by autocatalysis) (Bysimilarity). | Swiss-Prot 53.0 | 801 | Phosphotyrosine | 11741094 | Phospho.ELM 6.0 | 1214 | Phosphotyrosine (KDR) | 12023952;11387210 | Phospho.ELM 6.0 | 1175 | Phosphotyrosine (KDR) | 10579917;11387210;10749680;14532277 | Phospho.ELM 6.0 | 996 | Phosphotyrosine (KDR) | 10579917 | Phospho.ELM 6.0 | 1054 | Phosphotyrosine (KDR) | 10579917 | Phospho.ELM 6.0 | 1059 | Phosphotyrosine (KDR) | 10579917;11435426 | Phospho.ELM 6.0 | 951 | Phosphotyrosine (KDR) | 10579917;11435426 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr4 |
Promoter: 55686019 - 55688019 | Agilent_014791 |
chr4 |
Promoter: 55686019 - 55688019 | GoldenGate_Methylation_Cancer_Panel_I |
chr4 |
Promoter: 55686019 - 55688019 | GSE27584 |
chr4 |
Promoter: 55686019 - 55688019 | Agilent_014791_44K |