Epithelial-Mesenchymal Transition gene database (dbEMT) Home
dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

3589

Name

IL11

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription factors   [Top]

The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget

Links to the hTFtarget for IL11
Links to the AnimalTFDB for IL11

Regulation From TransFac database

IL-11(h) + MAGE11(h) <==> IL-11(h):MAGE11(h) (binding)
IL11(h) --> IL-11(h) (expression).
IL-1alpha(h) --> IL-11(h) (increase of secretion)
IL-1beta(h) --> IL-11(h) (increase of secretion)
TGFbeta1(h) --> IL-11(h) (increase of secretion)
TGFbeta2(h) --> IL-11(h) (increase of secretion)
TNF-alpha(h) --> IL-11(h) (increase of secretion)
IL-11(h) --> Ras(m):Raf(m.s.) (increase of binding)
IL-11(h) --> Fyn(m){pY} (increase of phosphorylation)
IL-11(h) --> Grb-2(m):Fyn(m){pY} (increase of binding)
IL-11(h) --> Jak2(m){pY} (increase of phosphorylation)
IL-11(h) --> Grb-2(m):Jak2(m){pY} (increase of binding)
IL-11(h) --> Fyn(m):Jak2(m){pY} (increase of binding)
IL-11(h) --> gp130(m):Jak2(m) (increase of binding)
IL-11(h) --> Cdh5(m) (transactivation)
IL-11(h) --> Pecam1(m) (transactivation)
IL-11(h) --> Kdr(m) (transactivation)
IL-11(h) --> STAT3(m){p} (increase of phosphorylation)
IL11(h) --> IL-11(h) (expression).

Post Translational Modification   [Top]

There is no record for IL11

Methylation Profile   [Top]

Chromosome

Location

Source

chr19

Promoter: 60573126 - 60575126GoldenGate_Methylation_Cancer_Panel_I

chr19

Promoter: 60573126 - 60575126GSE27584

chr19

Promoter: 60573126 - 60575126Agilent_014791_44K


')