| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3565 |
Name | IL4 |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for IL4 |
| Links to the AnimalTFDB for IL4 |
Regulation From TransFac database | IL-4(h) + IL-4Ralpha(h) <==> IL-4(h):IL-4Ralpha(h) (binding) | IL-4(h) + IL-4Ralpha(h) + IL-13Ralpha1(h) <==> IL-4(h):IL-4Ralpha(h):IL-13Ralpha1(h) (binding) | IL-4(h) --> Jak1(h){pY} (increase of phosphorylation) | IL-4(h) --> Jak3(h){pY} (increase of phosphorylation) | IL-4(h) --> STAT6(h){pY} (increase of phosphorylation) | IL-4(h) --> JNK1(h){p} (increase of phosphorylation) | IL-4(h) --> p38alpha(h){p} (increase of phosphorylation) | IL-4(h) --> ERK(h){p} (increase of phosphorylation) | IL-4(h) --> CS1(h) (increase of abundance) | IL-4(h) --> STAT3(h){pY705} (increase of phosphorylation) | IL-4(h) --> CRP(h) (transactivation) | IL-4(h) --> IL-4(h) (expression). | IFNgamma(h) --> IL-4(h) (increase of secretion) | IL-4-isoform1(h) --> STAT6(h){pS}{pY} (increase of phosphorylation) | IL-4-isoform1(h) --> STAT6(mo){pS}{pT}{pY} (increase of phosphorylation) | IL-4(h) --> IL-4-isoform1(h) (expression). | IL-4(h) --> IL-4-isoform2(h) (expression). |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 62 | N-linked (GlcNAc...). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr5 |
Promoter: 132035772 - 132037772 | GoldenGate_Methylation_Cancer_Panel_I |
chr5 |
Promoter: 132035772 - 132037772 | GoldenGate_Methylation_Cancer_Panel_I |
chr5 |
Promoter: 132035772 - 132037772 | GSE27584 |
chr5 |
Promoter: 132035772 - 132037772 | GSE27584 |