Epithelial-Mesenchymal Transition gene database (dbEMT) Home
dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

355

Name

FAS

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription factors   [Top]

The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget

Links to the hTFtarget for FAS
Links to the AnimalTFDB for FAS

Regulation From TransFac database

Fas(h) + FADD(h) <==> Fas(h):FADD(h) (binding)
Fas(h) + RIP(h) <==> Fas(h):RIP(h) (binding)
FasL(h) + Fas(h) <==> FasL(h):Fas(h) (binding)
Fas(h) + FAP-1(h) <==> Fas(h):FAP-1(h) (binding)
Fas(h) + FAP-1(m) <==> Fas(h):FAP-1(m) (binding)
c-Met(h) + Fas(h) <==> c-Met(h):Fas(h) (binding)
Fas(h) + sumo1(h) <==> Fas(h):sumo1(h) (binding)
c-FLIP-L-p43(h) + FADD(h) + Fas(h) + FasL(h) + proCaspase-8(h) <==> FasL(h):Fas(h):FADD(h):proCaspase-8(h):c-FLIP-L-p43(h) (binding)
Fas(h) + ASK1(h) <==> Fas(h):ASK1(h) (binding)
Fas(h) + Daxx(h) + ASK1(h) <==> Fas(h):Daxx(h):ASK1(h) (binding)
Fas(h) + FAF1(h) <==> Fas(h):FAF1(h) (binding)
proCaspase-8(h) + Fas(h) <==> Fas(h):proCaspase-8(h) (binding)
FADD(h) + FasL(h) + Fas(h) + proCaspase-10(h) <==> FADD(h):FasL(h):Fas(h):proCaspase-10(h) (binding)
proCaspase-10(h) + FADD(h) + Fas(h) <==> proCaspase-10(h):FADD(h):Fas(h) (binding)
FADD(h) + FasL(h) + Fas(h) <==> FADD(h):FasL(h):Fas(h) (binding)
Fas(h) + c-FLIP-L-p43(h) + Caspase-8a-p43(h) <==> Caspase-8a-p43(h):c-FLIP-L-p43(h):Fas(h) (binding)
Fas(h) + c-FLIP-L-p43(h) + Caspase-8b-p41(h) <==> c-FLIP-L-p43(h):Caspase-8b-p41(h):Fas(h) (binding)
FADD(h) + Fas(h) + c-FLIP-L-p43(h) <==> c-FLIP-L-p43(h):Fas(h):FADD(h) (binding)
Fas(h) + c-FLIP-L(h) <==> Fas(h):c-FLIP-L(h) (binding)
Fas(h) + Daxx(h) <==> Fas(h):Daxx(h) (binding)
Fas(h) --> c-FLIP(m) (binding)
Fas(h) --> TRAF1(h) (binding)
Fas(h) --> TRAF2(h) (binding)
Fas(h) --> Raf-1(h) (binding)
Fas(h) + Btk(h) <==> Fas(h):Btk(h) (binding)
c-FLIP-L-p43(h) + FADD(h) + Fas(h) + proCaspase-10(h) <==> c-FLIP-L-p43(h):FADD(h):Fas(h):proCaspase-10(h) (binding)
Fas(h) + FADD(m.s.) <==> Fas(h):FADD(m.s.) (binding)
Fas(h) --> proCaspase-8(h) (increase of processing)
Fas(h) --> proCaspase-3(h) (increase of processing)
c-FLIP-L-p43(h) + FADD(h) + Fas(h) + proCaspase-8(h) <==> c-FLIP-L-p43(h):FADD(h):Fas(h):proCaspase-8(h) (binding)
Fas(h) --> Bid(h) (increase of processing)
c-FLIP-L-p43(h) + FADD(h) + proCaspase-8(h) + Fas(h) <==> c-FLIP-L-p43(h):Fas(h):FADD(h):proCaspase-8(h) (binding)
Fas(h) + FasL(h) + c-FLIP-S(m.s.) + FADD(h) + proCaspase-8(h) + c-FLIP-L-p43(h) <==> Fas(h):FasL(h):c-FLIP-S(m.s.):FADD(h):proCaspase-8(h):c-FLIP-L-p43(h) (binding)
Fas(h) + FasL(h) + FADD(h) + Caspase-8-p43(h) + c-FLIP-L-p43(m.s.) <==> Fas(h):FasL(h):FADD(h):Caspase-8-p43(h):c-FLIP-L-p43(m.s.) (binding)
Fas(h) + Caspase-8-p43(h) + FADD(h) + RIP(h) + c-FLIP-L-p43(h) + c-FLIP-S(h) <==> Fas(h):Caspase-8-p43(h):FADD(h):RIP(h):c-FLIP-L-p43(h):c-FLIP-S(h) (binding)
Fas(h) + FADD(h) + proCaspase-8(h) + c-FLIP-p22(m.s.) <==> Fas(h):FADD(h):proCaspase-8(h):c-FLIP-p22(m.s.) (binding)
Fas(h) + FADD(h) + c-FLIP-L-p43(h) + Caspase-8-p18(h) <==> Fas(h):FADD(h):c-FLIP-L-p43(h):Caspase-8-p18(h) (binding)
Fas(h) + FADD(h) + c-FLIP-R(h) + c-FLIP-L-p43(h) + Caspase-8-p18(h) <==> Fas(h):FADD(h):c-FLIP-R(h):c-FLIP-L-p43(h):Caspase-8-p18(h) (binding)
Fas(h) + FADD(h) + c-FLIP-S(h) + c-FLIP-L-p43(h) + Caspase-8-p43(h) <==> Fas(h):FADD(h):c-FLIP-S(h):c-FLIP-L-p43(h):Caspase-8-p43(h) (binding)
Fas(h) + proCaspase-2(h) + Caspase-8-p43(h) <==> Fas(h):proCaspase-2(h):Caspase-8-p43(h) (binding)
Fas(h) + FADD(h) + Caspase-8-p18(h) + Caspase-2-p33(h) <==> Fas(h):FADD(h):Caspase-8-p18(h):Caspase-2-p33(h) (binding)
Fas(h) + FADD(h) + proCaspase-2(h) + Caspase-8-p43(h) <==> Fas(h):FADD(h):proCaspase-2(h):Caspase-8-p43(h) (binding)
Fas(h) + proCaspase-8(h) + Caspase-2-p33(h) <==> Fas(h):proCaspase-8(h):Caspase-2-p33(h) (binding)
Fas(h) + proCaspase-2(h) + proCaspase-8(h) <==> Fas(h):proCaspase-2(h):proCaspase-8(h) (binding)
Fas(h) + FADD(h) + proCaspase-8(h) <==> Fas(h):FADD(h):proCaspase-8(h) (binding)
Fas(h) + proCaspase-8(h) + FADD(h) <==> Fas(h):proCaspase-8(h):FADD(h) (binding)
Fas(h) + FADD(h) <==> Fas(h):FADD(h) (binding)
Fas(h) + p75NTR(h) <==> Fas(h):p75NTR(h) (binding)
Caspase-8-p43(h) + FasL(h) + FADD(h) + Fas(h) <==> Caspase-8-p43(h):FasL(h):FADD(h):Fas(h) (binding)
n Fas(h) <==> (Fas(h))n (oligomerization; binding)
c-FLIP-R(h) + c-FLIP-L(h) + proCaspase-8a(h) + FADD(h) + Fas(h) <==> c-FLIP-R(h):c-FLIP-L(h):proCaspase-8a(h):FADD(h):Fas(h) (binding)
c-FLIP-R(h) + c-FLIP-L(h) + proCaspase-8b(h) + FADD(h) + Fas(h) <==> c-FLIP-R(h):c-FLIP-L(h):proCaspase-8b(h):FADD(h):Fas(h) (binding)
c-FLIP-R(h) + c-FLIP-L-p43(h) + Caspase-8a-p43(h) + FADD(h) + Fas(h) <==> c-FLIP-R(h):c-FLIP-L-p43(h):Caspase-8a-p43(h):FADD(h):Fas(h) (binding)
c-FLIP-R(h) + c-FLIP-L-p43(h) + Caspase-8b-p41(h) + FADD(h) + Fas(h) <==> c-FLIP-R(h):c-FLIP-L-p43(h):Caspase-8b-p41(h):FADD(h):Fas(h) (binding)
c-FLIP-L(h) + proCaspase-8a(h) + Fas(h) <==> c-FLIP-L(h):proCaspase-8a(h):Fas(h) (binding)
c-FLIP-L(h) + proCaspase-8b(h) + Fas(h) <==> c-FLIP-L(h):proCaspase-8b(h):Fas(h) (binding)
c-FLIP-L-p43(h) + Caspase-8a-p43(h) + Fas(h) <==> c-FLIP-L-p43(h):Caspase-8a-p43(h):Fas(h) (binding)
Fas(h) + CRMP1(h) <==> Fas(h):CRMP1(h) (binding)
Fas(h) + EEF1A(h) <==> Fas(h):EEF1A(h) (binding)
FAS(h) --> Fas(h) (expression).
TNFR1(h) --> Fas(h) (binding)
Btk(h) --/ Fas(h) (inhibition)
amylin(h) --> Fas(h) (increase of abundance)
Apak(h) --/ Fas(h) (decrease of abundance)
FAS(h) --> Fas-isoform-1(h) (expression).
FAS(h) --> Fas-isoform-2(h) (expression).
FAS(h) --> Fas-isoform-3(h) (expression).
FAS(h) --> Fas-isoform-4(h) (expression).
FAS(h) --> Fas-isoform-5(h) (expression).
FAS(h) --> Fas-isoform-6(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

118N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
136N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr10

 Promoter: 90738768 - 90740768Agilent_014791

chr10

 Promoter: 90738768 - 90740768GoldenGate_Methylation_Cancer_Panel_I

chr10

 Promoter: 90738768 - 90740768GoldenGate_Methylation_Cancer_Panel_I

chr10

 Promoter: 90738768 - 90740768GoldenGate_Methylation_Cancer_Panel_I

chr10

 Promoter: 90738768 - 90740768GoldenGate_Methylation_Cancer_Panel_I

chr10

 Promoter: 90738768 - 90740768GoldenGate_Methylation_Cancer_Panel_I

chr10

 Promoter: 90738768 - 90740768GoldenGate_Methylation_Cancer_Panel_I

chr10

 Promoter: 90738768 - 90740768GoldenGate_Methylation_Cancer_Panel_I

chr10

 Promoter: 90738768 - 90740768GoldenGate_Methylation_Cancer_Panel_I

chr10

 Promoter: 90738768 - 90740768GSE27584

chr10

 Promoter: 90738768 - 90740768GSE27584

chr10

 Promoter: 90738768 - 90740768GSE27584

chr10

 Promoter: 90738768 - 90740768Agilent_014791_44K

chr10

 Promoter: 90738768 - 90740768Agilent_014791_44K

chr10

 Promoter: 90738768 - 90740768Agilent_014791_44K

chr10

 Promoter: 90738768 - 90740768Agilent_014791

chr10

 Promoter: 90738768 - 90740768PMID:20064646

chr10

 Promoter: 90738768 - 90740768PMID:20064646

chr10

 Promoter: 90738768 - 90740768PMID:20064646

chr10

 Promoter: 90738768 - 90740768PMID:20064646

chr10

 Promoter: 90738768 - 90740768PMID:20064646

chr10

 Promoter: 90738768 - 90740768PMID:20064646

chr10

 Promoter: 90738768 - 90740768PMID:20064646

chr10

 Promoter: 90738768 - 90740768PMID:20064646

chr10

 Promoter: 90738768 - 90740768PMID:12700649

chr10

 Promoter: 90738768 - 90740768PMID:12700649

chr10

 Promoter: 90738768 - 90740768PMID:12700649

chr10

 Promoter: 90738768 - 90740768PMID:12700649

chr10

 Promoter: 90738768 - 90740768PMID:12700649

chr10

 Promoter: 90738768 - 90740768PMID:12700649

chr10

 Promoter: 90738768 - 90740768PMID:12700649

chr10

 Promoter: 90738768 - 90740768PMID:12700649

chr10

 Promoter: 90738768 - 90740768PMID:11568974

chr10

 Promoter: 90738768 - 90740768PMID:11568974

chr10

 Promoter: 90738768 - 90740768PMID:11568974

chr10

 Promoter: 90738768 - 90740768PMID:11568974

chr10

 Promoter: 90738768 - 90740768PMID:11568974

chr10

 Promoter: 90738768 - 90740768PMID:11568974

chr10

 Promoter: 90738768 - 90740768PMID:11568974

chr10

 Promoter: 90738768 - 90740768PMID:11568974

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