| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3280 |
Name | HES1 |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for HES1 |
| Links to the AnimalTFDB for HES1 |
Regulation From TransFac database | HES-1(h) --/ MASH-1(h) (inhibition) | SIRT1(h) + HES-1(h) <==> SIRT1(h):HES-1(h) (binding) | HES-1(h) --> PTGDS(r) (DNA binding). | NICD1(h) --> HES-1(h) (activation) | NICD2(h) --> HES-1(h) (activation) | HES1(h) --> HES-1(h) (expression). | HES-1(h) + pRb(m.s.) <==> HES-1(h):pRb(m.s.) (binding) | AML3(m) + HES-1(h) <==> AML3(m):HES-1(h) (binding) | HES-1(h) + pRb(h) <==> HES-1(h):pRb(h) (binding) | HES-1(h) --/ PTGDS(h) (DNA binding; transrepression). | HES-1(h) --/ ASCL1(h) (DNA binding; transrepression). | HES-1(h) --/ REST(h) (DNA binding; transrepression). | HES-1(h) --> Hes1(r) (DNA binding). | HES-1(h) --> Rcor2(m) (DNA binding). | HES-1(h) --> GAA(h) (DNA binding; transactivation). | HES-1(h) --> GHR(h) (DNA binding). | HES1(h) --> HES-1(h) (expression). | EGF(m.s.) --/ HES-1(h) (decrease of abundance) | HES1(h) --> HES1(h) (expression). | hsa-miR-23a --/ HES1(h) (predicted) |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr3 |
Promoter: 195335128 - 195337128 | Agilent_014791 |
chr3 |
Promoter: 195335128 - 195337128 | GSE27584 |
chr3 |
Promoter: 195335128 - 195337128 | Agilent_014791_44K |