| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3082 |
Name | HGF |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for HGF |
| Links to the AnimalTFDB for HGF |
Regulation From TransFac database | HGF(h) + c-Met(m) <==> HGF(h):c-Met(m) (binding) | HGF(h) --> FOS(h) (transactivation) | HGF(h) --> ERK1(r){p} (increase of phosphorylation) | HGF(h) --> AKT(r){p} (increase of phosphorylation) | HGF(h) --> p38(r){p} (increase of phosphorylation) | HGF(h) --> TGIF(h) (increase of abundance) | HGF(h) --> TGIF(r) (increase of abundance) | HGF(h) --> ERK2(r){p} (increase of phosphorylation) | HGF(h) --> Sp1(h){pS} (increase of phosphorylation) | HGF(h) --> PKCdelta(h){p} (increase of phosphorylation) | HGF(h) --> VEGF-A(h) (increase of abundance) | HGF(h) --> VEGFA(h) (transactivation) | HGF(h) --> PKCzeta(h){pT410} (increase of phosphorylation) | HGF(h) --> AKT-1(h){pT308}{pS473} (increase of phosphorylation) | HGF(h) --> ERK1(h){pT202}{pY204} (increase of phosphorylation) | HGF(h) --> ERK2(h){pT185}{pY187} (increase of phosphorylation) | HGF(h) --> HGF(h) (expression). | HGF-isoform1(h) --> Gab-1(h):CrkL(h) (increase of binding) | HGF-isoform1(h) --> Gab-1(h):CrkL(h) (increase of binding) | HGF(h) --> HGF-isoform1(h) (expression). | HGF(h) --> HGF-isoform2(h) (expression). | HGF(h) --> HGF-isoform3(h) (expression). | HGF(h) --> HGF-isoform4(h) (expression). | HGF(h) --> HGF-isoform6(h) (expression). |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 32 | Pyrrolidone carboxylic acid. | Swiss-Prot 53.0 | 475 | O-linked | Shimizu N., Hara H., Sogabe T., Sakai H., Ihara I., Inoue H.,Nakamura T. and Shimizu S. (1992)Biochem. Biophys. Res. Commun., 189, 1329-1335. Medline: 93129192; | OGlycBase6.0 |
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Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr7 |
Promoter: 81236888 - 81238888 | GoldenGate_Methylation_Cancer_Panel_I |
chr7 |
Promoter: 81236888 - 81238888 | GoldenGate_Methylation_Cancer_Panel_I |
chr7 |
Promoter: 81236888 - 81238888 | GoldenGate_Methylation_Cancer_Panel_I |
chr7 |
Promoter: 81236888 - 81238888 | GoldenGate_Methylation_Cancer_Panel_I |
chr7 |
Promoter: 81236888 - 81238888 | GoldenGate_Methylation_Cancer_Panel_I |