| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3014 |
Name | H2AFX |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for H2AFX |
| Links to the AnimalTFDB for H2AFX |
Regulation From TransFac database | h2ax(h) + ATP --> h2ax(h){pS140} + ADP (phosphorylation) | h2ax(h) + ATP --> h2ax(h){p} + ADP (phosphorylation) | H2AFX(h) --> h2ax(h) (expression). | H2AFX(h) --> h2ax(h) (expression). | h2ax(h){pS140} --Wip1(m.s.)--> h2ax(h) + p (dephosphorylation) | h2ax(h){pS140} --> h2ax(h) + p (dephosphorylation) |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 2 | N-acetylserine (By similarity). | Swiss-Prot 53.0 | 2 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 140 | Phosphoserine (by ATM, ATR and PRKDC). | Swiss-Prot 53.0 | 120 | Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in ubiquitin) (Bysimilarity). | Swiss-Prot 53.0 | 139 | Phosphoserine (ATM) | 11571274 | Phospho.ELM 6.0 | 120 | Phosphothreonine | 16083285 | Phospho.ELM 6.0 | 123 | Phosphothreonine | 16083285 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr11 |
Promoter: 118470887 - 118472887 | Agilent_014791 |
chr11 |
Promoter: 118470887 - 118472887 | GSE27584 |
chr11 |
Promoter: 118470887 - 118472887 | Agilent_014791_44K |