Epithelial-Mesenchymal Transition gene database (dbEMT) Home
dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

2934

Name

GSN

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription factors   [Top]

The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget

Links to the hTFtarget for GSN
Links to the AnimalTFDB for GSN

Regulation From TransFac database

gelsolin(h) --Caspase-3(h)--> protein remnants (processing)
actin(h) + PLCgamma1(h) + gelsolin(h) <==> actin(h):PLCgamma1(h):gelsolin(h) (binding)
Caspase-4(h) + gelsolin(h) <==> Caspase-4(h):gelsolin(h) (binding)
PP2Cbeta(h) + gelsolin(h) <==> PP2Cbeta(h):gelsolin(h) (binding)
AR(h) + gelsolin(h) <==> AR(h):gelsolin(h) (binding)
GSN(h) --> gelsolin(h) (expression).
actin(h):PLCgamma1(h):gelsolin(h) <==> actin(h) + gelsolin(h) + PLCgamma1(h) (dissociation)
GSN(h) --> gelsolin-isoform1(h) (expression).
GSN(h) --> gelsolin-isoform2(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

86Phosphotyrosine; by SRC; in vitro.Swiss-Prot 53.0
409Phosphotyrosine; by SRC; in vitro.Swiss-Prot 53.0
465Phosphotyrosine (by SRC).Swiss-Prot 53.0
603Phosphotyrosine; by SRC; in vitro.Swiss-Prot 53.0
651Phosphotyrosine; by SRC; in vitro.Swiss-Prot 53.0
465Phosphotyrosine (Src)10210201Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr9

Promoter: 123100400 - 123102400Agilent_014791

chr9

Promoter: 123100400 - 123102400GSE27584

chr9

Promoter: 123068701 - 123070701GSE27584

chr9

Promoter: 123100400 - 123102400Agilent_014791_44K

chr9

Promoter: 123068701 - 123070701Agilent_014791_44K


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