| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2335 |
Name | FN1 |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for FN1 |
| Links to the AnimalTFDB for FN1 |
Regulation From TransFac database | LTBP1(h) + fibronectin(h) --TGC(gp)--> LTBP1(h):fibronectin(h) (oligomerization) | TGFbeta1(h):LAP(h):LTBP1(h) + fibronectin(h) --TGC(gp)--> TGFbeta1(h):LAP(h):LTBP1(h):fibronectin(h) (binding; assembly) | fibronectin(h) + CD11B(m.s.):beta2-integrin(h) <==> fibronectin(h):CD11B(m.s.):beta2-integrin(h) (binding) | CD11D(h):beta2-integrin(h) + fibronectin(h) <==> CD11D(h):beta2-integrin(h):fibronectin(h) (binding) | fibronectin(h) + CD11B(m) <==> fibronectin(h):CD11B(m) (binding) | fibronectin(h) + CD11D(m) <==> fibronectin(h):CD11D(m) (binding) | fibronectin(h) + CD11D(h) <==> fibronectin(h):CD11D(h) (binding) | fibronectin(h) --> FAK(h){p} (increase of phosphorylation) | fibronectin(h) --> p110alpha(h){pY} (increase of phosphorylation) | fibronectin(h) --> ERK1(h){p} (increase of phosphorylation) | fibronectin(h) --> ERK2(h){p} (increase of phosphorylation) | fibronectin(h) --> mmp2(h) (increase of abundance) | fibronectin(h) --> MT1-MMP(h) (increase of abundance) | fibronectin(h) + Keratin-19(h) <==> fibronectin(h):Keratin-19(h) (binding) | FN1(h) --> fibronectin(h) (expression). | TGFbeta2(h) --> fibronectin(h) (increase of abundance) | Dab2(h) --> fibronectin(h) (increase of abundance) | Dab2(m) --> fibronectin(h) (increase of abundance) | TGFbeta1(h) --> fibronectin(h) (increase of abundance) | EGF(m.s.) --> fibronectin(h) (increase of abundance) | FN1(h) --> fibronectin-xbb13(h) (expression). | FN1(h) --> fibronectin-1(h) (expression). | FN1(h) --> fibronectin-2(h) (expression). | FN1(h) --> fibronectin-3(h) (expression). | FN1(h) --> fibronectin-4(h) (expression). | FN1(h) --> fibronectin-5(h) (expression). | FN1(h) --> fibronectin-6(h) (expression). | FN1(h) --> fibronectin-7(h) (expression). | FN1(h) --> fibronectin-8(h) (expression). | FN1(h) --> fibronectin-9(h) (expression). | FN1(h) --> fibronectin-10(h) (expression). | FN1(h) --> fibronectin-11(h) (expression). | FN1(h) --> fibronectin-12(h) (expression). | FN1(h) --> fibronectin(h) (expression). | hsa-miR-199a* --/ fibronectin(h) (translational repression). |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 32 | Pyrrolidone carboxylic acid. | Swiss-Prot 53.0 | 430 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 528 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 542 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 876 | Sulfotyrosine (Potential). | Swiss-Prot 53.0 | 877 | N-linked (GlcNAc...) (By similarity). | Swiss-Prot 53.0 | 881 | Sulfotyrosine (Potential). | Swiss-Prot 53.0 | 1007 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 1244 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 2064 | O-linked (GalNAc...). | Swiss-Prot 53.0 | 2065 | O-linked (GalNAc...) (By similarity). | Swiss-Prot 53.0 | 2108 | N-linked (GlcNAc...) (By similarity). | Swiss-Prot 53.0 | 2384 | Phosphoserine. | Swiss-Prot 53.0 | 34 | Isoglutamyl lysine isopeptide (Gln-Lys)(interchain with K-?) (Probable). | Swiss-Prot 53.0 | 63 | Isoglutamyl lysine isopeptide (Gln-Lys)(interchain with K-?) (Probable). | Swiss-Prot 53.0 | 1443 | Isoglutamyl lysine isopeptide (Gln-Lys)(interchain with K-?) (Probable). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr2 |
Promoter: 216008536 - 216010536 | Agilent_014791 |
chr2 |
Promoter: 216008536 - 216010536 | GoldenGate_Methylation_Cancer_Panel_I |
chr2 |
Promoter: 216008536 - 216010536 | GoldenGate_Methylation_Cancer_Panel_I |
chr2 |
Promoter: 216008536 - 216010536 | GoldenGate_Methylation_Cancer_Panel_I |
chr2 |
Promoter: 216008536 - 216010536 | GoldenGate_Methylation_Cancer_Panel_I |
chr2 |
Promoter: 216008536 - 216010536 | GoldenGate_Methylation_Cancer_Panel_I |
chr2 |
Promoter: 216008536 - 216010536 | GoldenGate_Methylation_Cancer_Panel_I |
chr2 |
Promoter: 216008536 - 216010536 | GoldenGate_Methylation_Cancer_Panel_I |
chr2 |
Promoter: 216008536 - 216010536 | GSE27584 |
chr2 |
Promoter: 216008536 - 216010536 | GSE27584 |
chr2 |
Promoter: 216008536 - 216010536 | GSE27584 |
chr2 |
Promoter: 216008536 - 216010536 | GSE27584 |
chr2 |
Promoter: 216008536 - 216010536 | GSE27584 |
chr2 |
Promoter: 216008536 - 216010536 | GSE27584 |
chr2 |
Promoter: 216008536 - 216010536 | GSE27584 |
chr2 |
Promoter: 216008536 - 216010536 | Agilent_014791_44K |
chr2 |
Promoter: 216008536 - 216010536 | Agilent_014791_44K |
chr2 |
Promoter: 216008536 - 216010536 | Agilent_014791_44K |
chr2 |
Promoter: 216008536 - 216010536 | Agilent_014791_44K |
chr2 |
Promoter: 216008536 - 216010536 | Agilent_014791_44K |
chr2 |
Promoter: 216008536 - 216010536 | Agilent_014791_44K |
chr2 |
Promoter: 216008536 - 216010536 | Agilent_014791_44K |
chr2 |
Promoter: 216008536 - 216010536 | PMID:15911243 |
chr2 |
Promoter: 216008536 - 216010536 | PMID:15911243 |
chr2 |
Promoter: 216008536 - 216010536 | PMID:15911243 |
chr2 |
Promoter: 216008536 - 216010536 | PMID:15911243 |
chr2 |
Promoter: 216008536 - 216010536 | PMID:15911243 |
chr2 |
Promoter: 216008536 - 216010536 | PMID:15911243 |
chr2 |
Promoter: 216008536 - 216010536 | PMID:15911243 |