| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 22943 |
Name | DKK1 |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for DKK1 |
| Links to the AnimalTFDB for DKK1 |
Regulation From TransFac database | Dkk-1(h) + LRP6(h) <==> Dkk-1(h):LRP6(h) (binding) | Dkk-1(h) + CORO1(h) <==> Dkk-1(h):CORO1(h) (binding) | I-MF(h) + Dkk-1(h) <==> I-MF(h):Dkk-1(h) (binding) | DKK1(h) --> Dkk-1(h) (expression). | Dkk-1(h) --> KLEIP(h) (transactivation) | Dkk-1(h) --> KRT9(h) (transactivation) | Dkk-1(h) --> GJB6(h) (transactivation) | Dkk-1(h) --/ F2RL1(h) (transrepression) | Dkk-1(h) --/ P4HA2(h) (transrepression) | Dkk-1(h) --/ TULP3(h) (transrepression) | Dkk-1(h) --/ MITF(h) (transrepression) | Dkk-1(h) --> Keratin-9(h) (increase of abundance) | Dkk-1(h) --> kleip(h) (increase of abundance) | Dkk-1(h) --/ GSK3beta(h) (decrease of abundance) | Dkk-1(h) --/ PAR2(h) (decrease of abundance) | Dkk-1(h) --> PRKCB1(h) (transactivation) | Dkk-1(h) --> KRTAP5-9(h) (transactivation) | Dkk-1(h) --> GPR51(h) (transactivation) | Dkk-1(h) --> LRP6(h) (transactivation) | Dkk-1(h) --> GADD45A(h) (transactivation) | Dkk-1(h) --/ beta-catenin(h) (decrease of abundance) | Dkk-1(h) --> LDLR(h) (transactivation) | Dkk-1(h) --> GSK3beta(h){pS9} (increase of phosphorylation) | Dkk-1(h) --> PKCalpha(h) (increase of abundance) | Dkk-1(h) --/ melanin (decrease of abundance) | DKK1(h) --> Dkk-1(h) (expression). |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 256 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr10 |
Promoter: 53742547 - 53744547 | Agilent_014791 |
chr10 |
Promoter: 53742547 - 53744547 | GSE27584 |
chr10 |
Promoter: 53742547 - 53744547 | Agilent_014791_44K |
chr10 |
Promoter: 53742547 - 53744547 | Agilent_014791 |
chr10 |
Promoter: 53742547 - 53744547 | PMID:21304055 |
chr10 |
Promoter: 53742547 - 53744547 | PMID:16491118 |
chr10 |
Promoter: 53742547 - 53744547 | PMID:16671088 |