| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 208 |
Name | AKT2 |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for AKT2 |
| Links to the AnimalTFDB for AKT2 |
Regulation From TransFac database | AKT-2(h) + XIAP(h) <==> AKT-2(h):XIAP(h) (binding) | AKT-2(h) + ATP --> AKT-2(h){pS474} + ADP (phosphorylation) | AKT2(h) --> AKT-2(h) (expression). | XIAP(h) + NTP --AKT-2(h)--> XIAP(h){pS87} + NDP (phosphorylation) | AKT-2(h) --Caspase-3(h)--> AKT-2-p51(h) + protein remnants (cleavage) | AKT-2(h) + ATP --> AKT-2(h){pS474} + ADP (phosphorylation) | AKT-2(h) + APPL(m.s.) <==> AKT-2(h):APPL(m.s.) (binding) | AKT2(h) --> AKT-2(h) (expression). | ERR1(h) + ATP --AKT-2(h)--> ERR1(h){p} + ADP (phosphorylation) |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 309 | Phosphothreonine (by PDPK1). | Swiss-Prot 53.0 | 474 | Phosphoserine. | Swiss-Prot 53.0 | 309 | Phosphothreonine (PDK-1) | 9512493 | Phospho.ELM 6.0 | 126 | Phosphoserine | 9374542 | Phospho.ELM 6.0 | 451 | Phosphothreonine | 9374542 | Phospho.ELM 6.0 | 474 | Phosphoserine | 9374542;10822383 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr19 |
Promoter: 45482534 - 45484534 | Agilent_014791 |
chr19 |
Promoter: 45482534 - 45484534 | GSE27584 |
chr19 |
Promoter: 45482534 - 45484534 | Agilent_014791_44K |
chr19 |
Promoter: 45482534 - 45484534 | Agilent_014791 |