Epithelial-Mesenchymal Transition gene database (dbEMT) Home
dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

2056

Name

EPO

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription factors   [Top]

The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget

Links to the hTFtarget for EPO
Links to the AnimalTFDB for EPO

Regulation From TransFac database

Epo(h) + EpoR(h) <==> Epo(h):EpoR(h) (binding)
Epo(h) + 2 EpoR(h) <==> Epo(h):(EpoR(h))2 (binding)
Epo(h) --> Epo(h) (expression).
Epo(h) --> AKT(m){pT308} (increase of phosphorylation)
Epo(h) --> PLCgamma2(m){pY} (increase of phosphorylation)
Epo(h) --> STAT3(m):STAT3(m) (increase of binding)
Epo(h) --> SHP-2(h){pY} (increase of phosphorylation)
Epo(h) --> Epo(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

153O-linked (GalNAc...).Swiss-Prot 53.0
153O-linkedTakeuchi, M. and Kobata, A. (1991) Glycobiology, 1, 337-346.OGlycBase6.0
51N-likedTakeuchi, M. and Kobata, A. (1991) Glycobiology, 1, 337-346.OGlycBase6.0
65N-likedTakeuchi, M. and Kobata, A. (1991) Glycobiology, 1, 337-346.OGlycBase6.0
110N-likedTakeuchi, M. and Kobata, A. (1991) Glycobiology, 1, 337-346.OGlycBase6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr7

Promoter: 100154859 - 100156859Agilent_014791

chr7

Promoter: 100154859 - 100156859GoldenGate_Methylation_Cancer_Panel_I

chr7

Promoter: 100154859 - 100156859GSE27584


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