| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 1965 |
Name | EIF2S1 |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for EIF2S1 |
| Links to the AnimalTFDB for EIF2S1 |
Regulation From TransFac database | EIF-2alpha(h) + ATP --PKR(h)--> ADP + EIF-2alpha(h){p} (phosphorylation) | EIF2S1(h) --> EIF-2alpha(h) (expression). | EIF-2alpha(h) + ATP --> EIF-2alpha(h){p} + ADP (phosphorylation) | eIF1b(h) + EIF-2alpha(h) <==> eIF1b(h):EIF-2alpha(h) (binding) | eif5(h) + EIF-2alpha(h) <==> eif5(h):EIF-2alpha(h) (binding) | EIF-2alpha(h) + ATP --> EIF-2alpha(h){pS51} + ADP (phosphorylation) | EIF2S1(h) --> EIF-2alpha(h) (expression). |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 49 | Phosphoserine (by HRI) (By similarity). | Swiss-Prot 53.0 | 52 | Phosphoserine (by EIF2AK3, GCN2, HRI andPKR) (By similarity). | Swiss-Prot 53.0 | 48 | Phosphoserine (HRI;EIF2AK2) | 3352609;16288713 | Phospho.ELM 6.0 | 51 | Phosphoserine (HRI;EIF2AK2) | 3352609;9930704;11337501 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr14 |
Promoter: 66895287 - 66897287 | GSE27584 |
chr14 |
Promoter: 66895287 - 66897287 | Agilent_014791_44K |