Epithelial-Mesenchymal Transition gene database (dbEMT) Home
dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

1445

Name

CSK

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription factors   [Top]

The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget

Links to the hTFtarget for CSK
Links to the AnimalTFDB for CSK

Regulation From TransFac database

alpha IIb-integrin(h):beta3-integrin(h) + Csk(h) <==> alpha IIb-integrin(h):beta3-integrin(h):Csk(h) (binding)
Csk(h) + LIME(h){pY} <==> Csk(h):LIME(h){pY} (binding)
VE-cadherin(h) + Csk(h) <==> VE-cadherin(h):Csk(h) (binding)
GSK3beta(m) + Csk(h) <==> GSK3beta(m):Csk(h) (binding)
paxillin(h){pY} + Csk(h) <==> paxillin(h){pY}:Csk(h) (binding)
CD244(m.s.){pY} + Csk(h) <==> CD244(m.s.){pY}:Csk(h) (binding)
PTP-PEST(h) + Csk(h) <==> PTP-PEST(h):Csk(h) (binding)
CSK(h) --> Csk(h) (expression).
Fibrinogen(h) + alpha IIb-integrin(h):beta3-integrin(h):Csk(h) <==> Fibrinogen(h):alpha IIb-integrin(h):beta3-integrin(h) + Csk(h) (binding; dissociation)
Src(h) + ATP --Csk(h)--> Src(h){pY530} + ADP (phosphorylation)
Lck(h) + ATP --Csk(h)--> Lck(h){pY505} + ADP (phosphorylation)
CSK(h) --> Csk(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

184Phosphotyrosine.Swiss-Prot 53.0
304Phosphotyrosine; in vitro.Swiss-Prot 53.0
416Phosphotyrosine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
184Phosphotyrosine9148770Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr15

Promoter: 72860268 - 72862268Agilent_014791

chr15

Promoter: 72860268 - 72862268GoldenGate_Methylation_Cancer_Panel_I

chr15

Promoter: 72860268 - 72862268GSE27584

chr15

Promoter: 72860268 - 72862268Agilent_014791_44K


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