| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 10454 |
Name | TAB1 |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription factors [Top] |
The investigation of TF-target regulations in human from AnimalTFDB 3.0 database and hTFtarget |
|---|
| Links to the hTFtarget for TAB1 |
| Links to the AnimalTFDB for TAB1 |
Regulation From TransFac database | BMPR-IA(h) + TAB1(h) + XIAP(h) <==> BMPR-IA(h):XIAP(h):TAB1(h) (binding) | TAB1(h) + XIAP(h) <==> XIAP(h):TAB1(h) (binding) | TAB1(h) + TAK1(m) <==> TAB1(h):TAK1(m) (binding) | TRAF6(h) + TAB1(h) + TAK1(h) <==> TRAF6(h):TAB1(h):TAK1(h) (binding) | TAB1(h) + TAK1a(h) <==> TAB1(h):TAK1a(h) (binding) | TAK1(h) + TAB1(h) <==> TAK1(h):TAB1(h) (binding) | Smad7(h) + TAK1(h) + TAB1(h) <==> Smad7(h):TAK1(h):TAB1(h) (binding) | RANK(h) + TAK1(h) + TAB1(h) <==> RANK(h):TAK1(h):TAB1(h) (binding) | TAB1(h) + p38alpha(h) <==> TAB1(h):p38alpha(h) (binding) | TAB3(h) + TAK1(h) + TAB1(h) <==> TAB3(h):TAK1(h):TAB1(h) (binding) | TAB1(h) + p38alpha(m.s.) <==> TAB1(h):p38alpha(m.s.) (binding) | TAB1(h) + p38(h){p} <==> TAB1(h):p38(h){p} (binding) | TAB2(h) + TAB1(h) + TAK1(h) <==> TAB2(h):TAB1(h):TAK1(h) (binding) | TAB1(h) + TAK1(h){pT187} <==> TAB1(h):TAK1(h){pT187} (binding) | TAB1(h) --> TAB1(h) (expression). | TAB1(h):p38alpha(h) + NTP --> TAB1(h) + p38alpha(h){p} + NDP (phosphorylation; dissociation) | TAB1(h) --> TAK1(h){pT187} (increase of phosphorylation) | TAB1(h) + 3 ATP --p38alpha(h)--> TAB1(h){pS423}{pT431}{pS438} + 3 ADP (phosphorylation) | TAB1(h) + 3 ATP --p38beta(h)--> TAB1(h){pS423}{pT431}{pS438} + 3 ADP (phosphorylation) | TAB1(h) + 2 ATP --JNK1alpha1(h)--> TAB1(h){pT431}{pS438} + 2 ADP (phosphorylation) | TAB1(h) + 2 ATP --JNK2alpha-2(h)--> TAB1(h){pT431}{pS438} + 2 ADP (phosphorylation) | TAB1(h) + 2 ATP --ERK2(h)--> TAB1(h){pT431}{pS438} + 2 ADP (phosphorylation) | TAB1(h) + 2 ATP --p38gamma(h)--> TAB1(h){pT431}{pS438} + 2 ADP (phosphorylation) | TAB1(h) + 3 ATP --p38delta(h)--> TAB1(h){pS423}{pT431}{pS438} + 3 ADP (phosphorylation) | TAK1(m.s.) + TAB1(h) <==> TAK1(m.s.):TAB1(h) (binding) | TAB1(h) --> TAK1a(h){ubK158}n (increase of ubiquitination) | TAB1(h) --> TAK1a(h){ub{K63}(n)K158} (increase of ubiquitination) | TAB1(h) --> TAK1a(h){pT187} (increase of phosphorylation) | TAB1(h) --> MKK6(m.s.){p} (increase of phosphorylation) | TAB1(h) --> TAB1(h) (expression). | p38alpha(m.s.) + TAB1beta(h) <==> p38alpha(m.s.):TAB1beta(h) (binding) | p38gamma(m.s.) + TAB1beta(h) <==> p38gamma(m.s.):TAB1beta(h) (binding) | TAB1(h) --> TAB1beta(h) (expression). |
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 423 | Phosphoserine (MAPK14) | 14592977 | Phospho.ELM 6.0 | 431 | Phosphothreonine (MAPK14) | 14592977 | Phospho.ELM 6.0 | 438 | Phosphoserine (MAPK14) | 14592977 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr22 |
Promoter: 38124205 - 38126205 | GSE27584 |
chr22 |
Promoter: 38124205 - 38126205 | GSE27584 |
chr22 |
Promoter: 38124205 - 38126205 | Agilent_014791_44K |